Evidence map›Paper›PMID 30708983›Full record

ArticleMolecules (Basel, Switzerland)2019

Evaluation of the Hepatotoxicity of the Zhi-Zi-Hou-Po Decoction by Combining UPLC-Q-Exactive-MS-Based Metabolomics and HPLC-MS/MS-Based Geniposide Tissue Distribution.

Yunji Wang, Fang Feng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

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  13. Toxicity and Its Mechanism Study ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  14. The Effects of Different Varieties ofMolecules (Basel, Switzerland) · 2019
    Article
  15. Screening of the Hepatotoxic Components inMolecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yunji WangKey Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China. wangyunji1984@126.com.
Fang FengKey Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China. fengfang1@hotmail.com.
China Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With traditional Chinese medicine (TCM) becoming widespread globally, its safety has increasingly become a concern, especially its hepatoxicity. For example,

Indexed as

MetabolomeMetabolomicsAnimalsBiomarkersChemical and Drug Induced Liver InjuryChromatography, High Pressure LiquidComputational BiologyDisease Models, AnimalDrugs, Chinese HerbalIridoidsLiverMetabolic Networks and PathwaysRatsReproducibility of ResultsTandem Mass SpectrometryTissue DistributionBiomarkersDrugs, Chinese HerbalgeniposideIridoidsZhi-Zi-Hou-Pu decoctiongeniposidehepatotoxicitymetabonomicstissue distributionZhi-Zi-Hou-Po decoction

Identifiers

PMID30708983
PMCPMC6384998
OpenAlexW2913921801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.