ArticlePloS one2019
The association between exposure to different aspects of shift work and metabolic risk factors in health care workers, and the role of chronotype.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Exploring the Relationship between Chronotype and Waist Circumference: A Scoping Review.Sleep science (Sao Paulo, Brazil) · 2025Review
- Impact of sleep chronotype on blood pressure and metabolic markers.Frontiers in neurology · 2025Article
- Personalized sleep and nutritional strategies to combat adverse effects of night shift work: a controlled intervention protocol.BMC public health · 2024Article
- The Impact of Night Work on the Sleep and Health of Medical Staff-A Review of the Latest Scientific Reports.Journal of clinical medicine · 2024Review
- Investigating the relationship between shift work schedule and blood and metabolic parameters: a 10-years retrospective cohort study.Scientific reports · 2024Article
- Article
- Prospective study of the association between chronotype and cardiometabolic risk among Chinese young adults.BMC public health · 2023Article
- Consequences of Shift Work and Night Work: A Literature Review.Healthcare (Basel, Switzerland) · 2023Review
- Associations between circadian disruption and cardiometabolic disease risk: A review.Obesity (Silver Spring, Md.) · 2023Review
- Chronic blue light-emitting diode exposure harvests gut dysbiosis related to cholesterol dysregulation.Frontiers in cellular and infection microbiology · 2023Article
- Influence of shift work on cardiovascular disease risk in Southern African long-distance truck drivers: a cross-sectional study.BMJ open · 2022Article
- Night shift work characteristics are associated with several elevated metabolic risk factors and immune cell counts in a cross-sectional study.Scientific reports · 2022Article
- Shift Work Predicts Increases in Lipopolysaccharide-Binding Protein, Interleukin-10, and Leukocyte Counts in a Cross-Sectional Study of Healthy Volunteers Carrying Low-Grade Systemic Inflammation.International journal of environmental research and public health · 2021Article
- Review
- Immunological effects of shift work in healthcare workers.Scientific reports · 2019Article
- A cross-sectional study on serum high-sensitivity C-reactive protein level and shift work among reproductive age women.Caspian journal of internal medicine · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveShift work has been linked to cardio-metabolic diseases, but insight into different shift work-related aspects and chronotype of shift workers and their relation with metabolic risk factors is limited. This study examined the association between current shift work status, frequency and duration of night shift work, chronotype, and metabolic risk factors in a population of health care workers.
methodsAnthropometrics, questionnaires, and blood samples were collected from 503 shift working and 93 non-shift working health care workers employed in hospitals. Body mass index, waist circumference, cholesterol (total, HDL, LDL), triglycerides, and high-sensitivity C-reactive protein were measured. Associations of current shift work, frequency (non-night shift worker, 1-2, 3-4, ≥5 night shifts/month) and duration of night shift work (non-night shift workers, <10, 10-19, ≥20 years), and shift workers' chronotype, with metabolic risk factors were studied using linear regression analysis.
resultsCompared to non-shift workers, shift workers' total cholesterol level was 0.38 mmol/L lower (95%-CI = -0.73 --0.04) and LDL cholesterol was 0.34 mmol/L lower (95%-CI = -0.60 --0.08). For all other metabolic risk factors, no differences were found. The association between shift work and LDL cholesterol was especially found among shift workers working night shifts for ≥20 years (B = -0.49 (95%-CI = -0.78 --0.19)). No differences were found for night shift frequency and chronotype.
conclusionIn this population of health care workers employed in hospitals, no evidence for differences in metabolic risk factors was observed that could underlie a link between shift work and cardio-metabolic diseases. Further research using different aspects of shift work to study the association with metabolic risk factors is recommended.
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