Evidence map›Paper›PMID 30707624›Full record

ArticleLGBT health

Psychiatric Epidemiology of Transgender and Nonbinary Adult Patients at an Urban Health Center.

Noor Beckwith, Michal J McDowell, Sari L Reisner, Shayne Zaslow, Roger D Weiss, Kenneth H Mayer, Alex S Keuroghlian

Abstract read
In one paragraph

Article in LGBT health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Gender Differences and Comorbidities in Major Depression.Advances in experimental medicine and biology · 2026
    Review
  5. Article
  6. Article
  7. Mental Health Outcomes AmongInternational journal of environmental research and public health · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Providing Care for Transgender Persons With Kidney Disease: A Narrative Review.Canadian journal of kidney health and disease · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noor Beckwith1 Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Michal J McDowell1 Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Sari L Reisner2 Harvard Medical School, Boston, Massachusetts.
Shayne Zaslow3 The Fenway Institute, Fenway Health, Boston, Massachusetts.
Roger D Weiss2 Harvard Medical School, Boston, Massachusetts.
Kenneth H Mayer2 Harvard Medical School, Boston, Massachusetts.
Alex S Keuroghlian1 Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.

Funding

Fostering Research Mentorship & Training during Psychiatry Residency SupplementR25MH094612 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FAVA, MAURIZIO, GREENFIELD, SHELLY F. · 2011 to 2022
$2.3M
Mentoring in Drug Abuse and Dual Diagnosis ResearchK24DA022288 · NIDA · MCLEAN HOSPITAL · PI WEISS, ROGER D. · 2007 to 2016
$1.8M
TransPrEP: Social Network-Based PrEP Adherence for Transgender Women in PeruR34MH104072 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CLARK, JESSE LAWTON, MIMIAGA, MATTHEW JAMES · 2014 to 2016
$672k
NIDA NIH HHS K24 DA022288NIMH NIH HHS R25 MH094612NIMH NIH HHS R34 MH104072
6 · The paper itself

Abstract

purposeTransgender and nonbinary people have an increased burden of psychiatric problems compared with the general population. Data are needed to understand factors associated with psychiatric diagnoses, acuity in terms of suicide attempts and level-of-care escalation, and outpatient engagement among transgender and nonbinary adults.

methodsWe conducted a retrospective review of records from 201 transgender and nonbinary adults who presented for primary care at a health center. Regression models were fit to examine factors associated with psychiatric diagnoses, substance use disorders (SUDs), acuity, and outpatient behavioral health engagement.

resultsMale sex assignment at birth was associated with decreased odds of a psychiatric diagnosis (odds ratio [OR] 0.40, 95% confidence interval [CI]: 0.20-0.81). Increased odds of SUDs were associated with later hormone initiation (OR 1.04, 95% CI: 1.01-1.08) and suicide attempt (OR 5.79, 95% CI: 2.08-16.15). Increased odds of higher acuity were associated with alcohol use disorder (OR 31.54, 95% CI: 5.73-173.51), post-traumatic stress disorder (OR 18.14, 95% CI: 2.62-125.71), major depressive disorder (MDD) (OR 6.62, 95% CI: 1.72-25.44), and absence of psychiatrist integration into primary medical care (OR 4.52, 95% CI: 1.26-16.22). Increased odds of outpatient behavioral health engagement were associated with case management utilization (OR 10.73, 95% CI: 1.32-87.53), anxiety disorders (OR 15.84, 95% CI: 2.00-125.72), and MDD (OR 10.45, 95% CI: 2.28-47.98).

conclusionPsychiatric disorders were highly prevalent among transgender and nonbinary adult patients. Novel findings include associations of lack of psychiatrist integration into primary care with acuity and of case management utilization with outpatient behavioral health engagement.

Indexed as

Primary Health CareAdultAlcoholismAmbulatory CareAnxiety DisordersCase ManagementDelivery of Health CareFemaleGender-Affirming ProceduresGonadal Steroid HormonesHumansMajor Depressive DisorderMaleMental DisordersMental Health ServicesMiddle AgedGonadal Steroid Hormonesmental healthminority stressnonbinarysubstance use disorderssuicidetransgender

Identifiers

PMID30707624
PMCPMC6434596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.