Evidence map›Paper›PMID 30707105›Full record

ArticleJMIR research protocols2019

Artificial Intelligence for the Detection of Diabetic Retinopathy in Primary Care: Protocol for Algorithm Development.

Josep Vidal-Alaball, Dídac Royo Fibla, Miguel A Zapata, Francesc X Marin-Gomez, Oscar Solans Fernandez

Abstract read
In one paragraph

Article in JMIR research protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Frontiers in psychiatry · 2024
    Review
  3. Article
  4. Article
  5. Artificial intelligence and Psychiatry: An overview.Asian journal of psychiatry · 2022
    Review
  6. Multi-label classification of retinal lesions in diabetic retinopathy for automatic analysis of fundus fluorescein angiography based on deep learning.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Josep Vidal-AlaballHealth Promotion in Rural Areas Research Group, Gerència Territorial de la Catalunya Central, Catalan Health Institute, Sant Fruitós de Bages, Spain.ORCID http://orcid.org/0000-0002-3527-4242
Dídac Royo FiblaOPTretina, Sant Cugat del Vallès, Spain.ORCID http://orcid.org/0000-0002-4183-4971
Miguel A ZapataOPTretina, Sant Cugat del Vallès, Spain.ORCID http://orcid.org/0000-0002-0096-4569
Francesc X Marin-GomezHealth Promotion in Rural Areas Research Group, Gerència Territorial de la Catalunya Central, Catalan Health Institute, Sant Fruitós de Bages, Spain.ORCID http://orcid.org/0000-0002-6749-0468
Oscar Solans FernandezeHealth Directorate, Department of Health, Government of Catalonia, Barcelona, Spain.ORCID http://orcid.org/0000-0002-3822-9869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic retinopathy (DR) is one of the most important causes of blindness worldwide, especially in developed countries. In diabetic patients, periodic examination of the back of the eye using a nonmydriatic camera has been widely demonstrated to be an effective system to control and prevent the onset of DR. Convolutional neural networks have been used to detect DR, achieving very high sensitivities and specificities.

objectiveThe objective of this is paper was to develop an artificial intelligence (AI) algorithm for the detection of signs of DR in diabetic patients and to scientifically validate the algorithm to be used as a screening tool in primary care.

methodsUnder this project, 2 studies will be conducted in a concomitant way: (1) Development of an algorithm with AI to detect signs of DR in patients with diabetes and (2) A prospective study comparing the diagnostic capacity of the AI algorithm with respect to the actual system of family physicians evaluating the images. The standard reference to compare with will be a blinded double reading conducted by retina specialists. For the development of the AI algorithm, different iterations and workouts will be performed on the same set of data. Before starting each new workout, the strategy of dividing the set date into 2 groups will be used randomly. A group with 80% of the images will be used during the training (training dataset), and the remaining 20% images will be used to validate the results (validation dataset) of each cycle (epoch). During the prospective study, true-positive, true-negative, false-positive, and false-negative values will be calculated again. From here, we will obtain the resulting confusion matrix and other indicators to measure the performance of the algorithm.

resultsCession of the images began at the end of 2018. The development of the AI algorithm is calculated to last about 3 to 4 months. Inclusion of patients in the cohort will start in early 2019 and is expected to last 3 to 4 months. Preliminary results are expected to be published by the end of 2019.

conclusionsThe study will allow the development of an algorithm based on AI that can demonstrate an equal or superior performance, and that constitutes a complement or an alternative, to the current screening of DR in diabetic patients. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/12539.

Indexed as

artificial intelligencecomputer assisted diagnosisdiabetes mellitusdiabetic retinopathyfundus oculineural network computer

Identifiers

PMID30707105
PMCPMC6376335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.