Observational studyCurrent neurovascular research2019
Changes in Cognition, Depression and Quality of Life after Carotid Stenosis Treatment.
Observational study in Current neurovascular research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Cognitive impairment and quality of life among patients with carotid artery stenosis in Jordan: a cross-sectional study.Scientific reports · 2025Article
- Carotid Revascularization Is Associated With Improved Mood in Patients With Advanced Carotid Disease.Annals of surgery · 2025Article
- Carotid revascularization improves cognition in patients with carotid stenosis.Scientific reports · 2025Article
- Cognitive Impairment is Common and Unrecognized in Vascular Surgery Patients.Annals of vascular surgery · 2025Observational
- Article
- Cognitive functions and sense of coherence in patients with carotid artery stenosis-Preliminary report.Frontiers in psychiatry · 2023Article
- Cognitive Functions after Carotid Artery Stenting-1-Year Follow-Up Study.Journal of clinical medicine · 2022Article
- Differential Cognitive Functioning and Benefit From Surgery in Patients Undergoing Coronary Artery Bypass Grafting and Carotid Endarterectomy.Frontiers in neurology · 2022Article
- Cognitive Functions in Patients after Carotid Artery Revascularization-A Narrative Review.Brain sciences · 2021Review
- Revascularization for asymptomatic carotid artery stenosis improves balance and mobility.Journal of vascular surgery · 2021Article
- Early Age of Migraine Onset is Independently Related to Cognitive Decline and Symptoms of Depression Affect Quality of Life.Current neurovascular research · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough several studies have evaluated the change of cognitive performance after severe carotid artery stenosis, the results still remain elusive. The objective of this study was to assess changes in cognitive function, depressive symptoms and Health Related Quality of Life (HRQoL) after carotid stenosis revascularisation and Best Medical Treatment (BMT).
methodsStudy involved 213 patients with ≥70% carotid stenosis who underwent assessment of cognitive function using Montreal Cognitive Assessment scale (MoCA), depressive symptoms - using Patient Health Questionnaire-9 (PHQ-9) and HRQoL - using Medical Outcome Survey Short Form version 2 (SF-36v2). The assessment was performed before and at 6 and 12 months followup periods in patients who had Carotid Endarterectomy (CEA), Carotid Artery Stenting (CAS) or received BMT only.
resultsImprovement in the total MoCA scores was observed after 6 and 12 months (p<0.001, Kendall's W=0.28) in the CEA group. In the CAS group - after 12 months (p=0.01, Kendall's W=0.261) whereas in the BMT group - no significant changes (p=0.295, Kendall's W=0.081) were observed. Reduction of depressive symptoms was not found in any of the study groups. Comparing mean SF-36v2 scores in the CEA group, there was no significant difference in any of 10 subscales. Likewise in the CAS group - no significant difference in 9 of 10 subscales (p=0.028, η2=0.343) was observed. Three subscales worsened in the BMT group during the 1-year follow-up period.
conclusionPatients with severe carotid stenosis who underwent revascularisation enhanced their cognitive performance without exerting significant change of depressive symptoms. Preoperative HRQoL may be maintained for at least one year in the CEA group.
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