Evidence map›Paper›PMID 30706614›Full record

ArticlePlant biotechnology journal2019

Development of an Agrobacterium-delivered CRISPR/Cas9 system for wheat genome editing.

Zhengzhi Zhang, Lei Hua, Ajay Gupta, David Tricoli, Keith J Edwards, Bing Yang, Wanlong Li

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

  1. Article
  2. Review
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  7. Review
  8. The Role ofInternational journal of molecular sciences · 2025
    Review
  9. CRISPR-Cas Gene Editing Technology in Potato.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Pigments to precision: RUBY aiding genetic transformation and genome editing in wheat and barley.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengzhi ZhangDivision of Plant Sciences, University of Missouri, Columbia, MO, USA.
Lei HuaDepartment of Biology and Microbiology, South Dakota State University, Brookings, SD, USA.
Ajay GuptaDepartment of Biology and Microbiology, South Dakota State University, Brookings, SD, USA.
David TricoliPlant Transformation Facility, University of California, Davis, CA, USA.
Keith J EdwardsFunctional Genomics, University of Bristol, Bristol, UK.
Bing YangDivision of Plant Sciences, University of Missouri, Columbia, MO, USA.
Wanlong LiDepartment of Biology and Microbiology, South Dakota State University, Brookings, SD, USA.ORCID 0000-0001-5886-1426

Funding

Biotechnology and Biological Sciences Research Council BB/L01386X/1
6 · The paper itself

Abstract

CRISPR/Cas9 has been widely used for genome editing in many organisms, including important crops like wheat. Despite the tractability in designing CRISPR/Cas9, efficacy in the application of this powerful genome editing tool also depends on DNA delivery methods. In wheat, the biolistics based transformation is the most used method for delivery of the CRISPR/Cas9 complex. Due to the high frequency of gene silencing associated with co-transferred plasmid backbone and low edit rate in wheat, a large T

Indexed as

CRISPR-Cas SystemsGene EditingAgrobacteriumGenome, PlantPlants, Genetically ModifiedPromoter Regions, GeneticRNA, Guide, CRISPR-Cas SystemsSequence DeletionTriticumRNA, Guide, CRISPR-Cas SystemsAgrobacterium mediationCRISPR/Cas9genome editinggrain regulation. mutationswheat

Identifiers

PMID30706614
PMCPMC6662106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.