Evidence map›Paper›PMID 30706470›Full record

Observational studyInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2019

Clinical presentation of pregnant women in isolation units for Ebola virus disease in Sierra Leone, 2014.

Jonetta J Mpofu, Fatma Soud, Meghan Lyman, Alimamy P Koroma, Diane Morof, Sascha Ellington, Samuel S Kargbo, William Callaghan

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Ebola virus disease in pregnancy: a systematic review and meta-analysis.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Pooled it
  2. Pooled it
  3. Review
  4. Atypical clinical presentation of Ebola virus disease in pregnancy: Implications for clinical and public health management.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Jonetta J MpofuDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Fatma SoudZambia Country Office, Centers for Disease Control and Prevention, Lusaka, Zambia.
Meghan LymanEpidemic Intelligence Service, Division of Scientific Education and Professional Development, Office of Public Health Scientific Services, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Alimamy P KoromaMinistry of Health and Sanitation, Freetown, Sierra Leone.
Diane MorofDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sascha EllingtonDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Samuel S KargboMinistry of Health and Sanitation, Freetown, Sierra Leone.
William CallaghanDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USCentre for Infectious Disease Research in Zambia · ZMMinistry of Health · BBMinistry of Health and Sanitation · SLNational Center for Chronic Disease Prevention and Health Promotion · USUnited States Public Health Service Commissioned Officers Association · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesTo examine Ebola virus disease (EVD) symptom prevalence and EVD status among pregnant women in Ebola isolation units in Sierra Leone.

methodsIn an observational study, data were obtained for pregnant women admitted to Ebola isolation units across four districts in Sierra Leone from June 29, 2014, to December 20, 2014. Women were admitted to isolation units if they had suspected EVD exposures or fever (temperature >38°C) and three or more self-reported symptoms suggestive of EVD. Associations were examined between EVD status and each symptom using χ

resultsOf 176 pregnant women isolated, 55 (32.5%) tested positive for EVD. Using logistic regression models adjusted for age, EVD-positive women were significantly more likely to have fever, self-reported fatigue/weakness, nausea/vomiting, headache, muscle/joint pain, chest pain, vaginal bleeding, unexplained bleeding, or sore throat upon admission. In models adjusted for age/labor, only women with fever or vaginal bleeding upon admission were significantly more likely to be EVD-positive.

conclusionsSeveral EVD symptoms and complications increased the odds of testing EVD-positive; some of these were also signs and symptoms of labor/pregnancy complications. The study results highlight the need to refine screening for pregnant women with EVD.

Indexed as

AdolescentAdultFatigueFemaleFeverHeadacheHemorrhageHemorrhagic Fever, EbolaHospitalizationHumansLogistic ModelsNauseaPatient IsolationPregnancyPregnancy Complications, InfectiousRetrospective StudiesEbola virus diseaseEbola virus infectionPregnancySierra LeoneSigns and symptomsSymptom assessment

Identifiers

PMID30706470
PMCPMC6507430
OpenAlexW2913954955

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.