Evidence map›Paper›PMID 30706217›Full record

ArticleAIDS and behavior2019

Pre-exposure Prophylaxis (PrEP) Awareness and Use Within High HIV Transmission Networks.

Kellie Schueler, Matthew Ferreira, Georgios Nikolopoulos, Britt Skaathun, Dimitrios Paraskevis, Angelos Hatzakis, Samuel R Friedman, John A Schneider

Abstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  5. Trial
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  15. Accounting for Context in Randomized Trials after Assignment.Prevention science : the official journal of the Society for Prevention Research · 2022
    Article
  16. Review
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  20. Intersection of Syphilis and Human Immunodeficiency Virus (HIV) Networks to Identify Opportunities to Enhance HIV Prevention.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kellie SchuelerPritzker School of Medicine, University of Chicago, 924 E 57th St, Suite 104, Chicago, IL, 60637, USA.
Matthew FerreiraChicago Center for HIV Elimination, University of Chicago, 5841 S Maryland Ave, MC5065, Chicago, IL, 60637, USA.
Georgios NikolopoulosMedical School, University of Cyprus, Nicosia, Cyprus.
Britt SkaathunDivision of Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA.
Dimitrios ParaskevisDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Angelos HatzakisDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Samuel R FriedmanNational Development and Research Institutes, New York City, NY, USA.
John A SchneiderPritzker School of Medicine, University of Chicago, 924 E 57th St, Suite 104, Chicago, IL, 60637, USA. jschnei1@medicine.bsd.uchicago.edu.ORCID http://orcid.org/0000-0002-7870-5639

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
HOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7M
Next-Generation Phylodynamics-targeted Partner Service Models for Combined HIV PreventionR01AI136056 · NIAID · UNIVERSITY OF CHICAGO · PI BENBOW, NANETTE DIOR, D'AQUILA, RICHARD · 2018 to 2022
$4.0M
Preventing HIV Transmission by Recently-Infected Drug UsersDP1DA034989 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI FRIEDMAN, SAMUEL R · 2012 to 2016
$3.8M
National Institute of Allergy and Infectious Diseases R01AI136056NIAID NIH HHS R01 AI136056NIAID NIH HHS T32 AI007384NIDA NIH HHS DP1 DA034989NIDA NIH HHS DP1DA034989-01NIDA NIH HHS P30 DA011041
6 · The paper itself

Abstract

Improved implementation of pre-exposure prophylaxis (PrEP) should be a valuable tool within communities experiencing high HIV incidence, such as black men who have sex with men (MSM). Using baseline data from the Chicago arm of the Transmission Reduction Intervention Project (TRIP), we examined awareness and use of PrEP within HIV potential transmission networks. Transmission Reduction Intervention Project recruited participants ages 18-69 (N = 218) during 2014-2016 from networks originating from recently and chronically HIV-infected MSM and transgender persons. In total, 53.2% of participants had heard of PrEP, while 8 (6.5%) HIV-negative participants reported ever using PrEP. In multivariable regression, PrEP awareness was associated with identifying as gay, attending some college or higher, having an HIV test in the previous 6 months, and experiencing HIV-related social support. PrEP awareness was not associated with experiencing or observing HIV-related stigma. PrEP use was associated with participants knowing two or more other PrEP-users. These findings demonstrate moderate awareness, but low uptake of PrEP within HIV potential transmission networks in Chicago. Future research should explore how to increase PrEP use in these networks and investigate the social dynamics behind our finding that PrEP users are more likely to know other PrEP users.

Indexed as

Homosexuality, MaleTransgender PersonsAdolescentAdultAgedAwarenessBlack or African AmericanChicagoFemaleHIV InfectionsHumansMaleMiddle AgedPre-Exposure ProphylaxisSafe SexSocial StigmaAfrican AmericanBlackHuman immunodeficiency virus (HIV)Men who have sex with men (MSM)Network analysisPre-exposure prophylaxis (PrEP)

Identifiers

PMID30706217
PMCPMC6800107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.