Evidence map›Paper›PMID 30706097›Full record

Trial reportPsychopharmacology2019

Catecholaminergic modulation of trust decisions.

Cătălina E Rățală, Sean J Fallon, Marieke E van der Schaaf, Niels Ter Huurne, Roshan Cools, Alan G Sanfey

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Trust learning in the repeated trust game: A meta-analytic study.British journal of psychology (London, England : 1953) · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cătălina E RățalăRotterdam School of Management, Erasmus University Rotterdam, Rotterdam, 3062, PA, The Netherlands. C.Ratala@donders.ru.nl.ORCID http://orcid.org/0000-0001-6301-4352
Sean J FallonDonders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University, 6500, HB, Nijmegen, The Netherlands.
Marieke E van der SchaafDonders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University, 6500, HB, Nijmegen, The Netherlands.
Niels Ter HuurneDonders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University, 6500, HB, Nijmegen, The Netherlands.
Roshan CoolsDonders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University, 6500, HB, Nijmegen, The Netherlands.
Alan G SanfeyDonders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University, 6500, HB, Nijmegen, The Netherlands.
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleTrust is a key component of social interactions. In order to assess the trustworthiness of others, people rely on both information learned from previous encounters, as well as on implicit biases associated with specific facial features.

objectiveHere, we investigated the role of catecholamine (dopamine and noradrenaline) transmission on trust decisions as a function of both experienced behavior and facial features.

methodsTo increase catecholamine levels, methylphenidate (MPH, i.e., Ritalin®, 20 mg) was administered to participants (N = 24) prior to their playing a well-studied economic task, namely the Trust Game (Berg et al. 1995). We measured the amount of money invested with a variety of game partners. Across game partners, we manipulated two aspects of trust: the facial trust level (high facial trust, low facial trust, and non-social) and the likelihood of reciprocation (high, low).

resultsResults demonstrated no main effect of MPH on investments, but rather a selective lowering of investments under MPH as compared with placebo with the game partners who were low on facial trustworthiness and were low reciprocators.

conclusionThese results provide evidence that MPH administration impacts social trust decision-making, but does so in a context-specific manner.

Indexed as

Facial ExpressionInterpersonal RelationsAdolescentCross-Over StudiesDecision MakingDopamineDopamine Uptake InhibitorsDouble-Blind MethodFemaleGames, ExperimentalHumansLearningMaleMethylphenidateNorepinephrineTrustDopamineDopamine Uptake InhibitorsMethylphenidateNorepinephrineCatecholaminesDecision-makingMethylphenidateRitalinSocial learningTrustTrust Game

Identifiers

PMID30706097
PMCPMC6602982
OpenAlexW2912897626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.