Evidence map›Paper›PMID 30706028›Full record

ArticleAdvances in radiation oncology

Big Data Readiness in Radiation Oncology: An Efficient Approach for Relabeling Radiation Therapy Structures With Their TG-263 Standard Name in Real-World Data Sets.

Thilo Schuler, John Kipritidis, Thomas Eade, George Hruby, Andrew Kneebone, Mario Perez, Kylie Grimberg, Kylie Richardson, Sally Evill, Brooke Evans and 1 more

Abstract read
In one paragraph

Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Educative Impact of Automatic Delineation Applied to Head and Neck Cancer Patients on Radiation Oncology Residents.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Technical Note: An open source solution for improving TG-263 compliance.Journal of applied clinical medical physics · 2019
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thilo SchulerDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
John KipritidisDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Thomas EadeDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
George HrubyDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Andrew KneeboneDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Mario PerezDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Kylie GrimbergDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Kylie RichardsonDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Sally EvillDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Brooke EvansDepartment of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, Australia.
Blanca GallegoAustralian Institute of Health Innovation, Macquarie University, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo prepare for big data analyses on radiation therapy data, we developed METHODS AND MATERIALS: The clinically relevant structures in the radiation therapy plans were identified by reference to randomized controlled trials. The Stature approach was used by clinicians to identify the synonyms for each relevant structure, which was then mapped to the corresponding TG-263 name. We applied Stature to standardize the structure names for 654 patients with prostate cancer (PCa) and 224 patients with head and neck squamous cell carcinoma (HNSCC) who received curative radiation therapy at our institution between 2007 and 2017. The accuracy of the Stature process was manually validated in a random sample from each cohort. For the HNSCC cohort we measured the resource requirements for Stature, and for the PCa cohort we demonstrated its impact on an example clinical analytics scenario.

resultsAll but 1 synonym group ("Hydrogel") was mapped to the corresponding TG-263 name, resulting in a TG-263 relabel rate of 99% (8837 of 8925 structures). For the PCa cohort, Stature matched a total of 5969 structures. Of these, 5682 structures were exact matches (ie, following local naming convention), 284 were matched via a synonym, and 3 required manual matching. This original radiation therapy structure names therefore had a naming inconsistency rate of 4.81%. For the HNSCC cohort, Stature mapped a total of 2956 structures (2638 exact, 304 synonym, 14 manual; 10.76% inconsistency rate) and required 7.5 clinician hours. The clinician hours required were one-fifth of those that would be required for manual relabeling. The accuracy of Stature was 99.97% (PCa) and 99.61% (HNSCC).

conclusionsThe Stature approach was highly accurate and had significant resource efficiencies compared with manual curation.

Identifiers

PMID30706028
PMCPMC6349627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.