Evidence map›Paper›PMID 30705933›Full record

ReviewPractical laboratory medicine2019

Biological function and molecular mechanism of piRNA in cancer.

Ghanbar Mahmoodi Chalbatani, Hassan Dana, Feridon Memari, Elahe Gharagozlou, Shirin Ashjaei, Peyman Kheirandish, Vahid Marmari, Habibollah Mahmoudzadeh, Farnaz Mozayani, Ali Reza Maleki and 9 more

Erratum issuedAbstract readReview
In one paragraph

Review in Practical laboratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Identification of piRNA disease associations using deep learning.Computational and structural biotechnology journal · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Ghanbar Mahmoodi ChalbataniCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Hassan DanaDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Feridon MemariCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Elahe GharagozlouCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Shirin AshjaeiDepartment of Paramedical Sciences, Islamic Azad University, Tehran Branch, Tehran, Iran.
Peyman KheirandishCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Vahid MarmariDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Habibollah MahmoudzadehCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Farnaz MozayaniCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Ali Reza MalekiCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Ehsan SadeghianCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Elham Zainali NiaDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Seyed Rohollah MiriCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Neda Zainali NiaDepartment of Biology, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.
Omid RezaeianDepartment of Biology, NourDanesh Institute of Higher Education, Isfahan, Iran.
Anahita EskandaryDepartment of Biology, NourDanesh Institute of Higher Education, Isfahan, Iran.
Narges RazaviShahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad ShirkhodaCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
Fatemeh Nouri RouzbahaniCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer genomics. In recent years, a relatively large number of studies have demonstrated that several piRNA are aberrantly expressed in various kinds of cancers including gastric cancer, bladder cancer, breast cancer, colorectal cancer and Lung cancer and may probably serve as a novel therapeutic target and biomarker for cancer treatment. The present review summarized current advances in our knowledge of the roles of piRNAs in cancer.

Indexed as

CancerGene silencingNoncoding RNAPiRNARNAi

Identifiers

PMID30705933
PMCPMC6349561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.