ArticleRespiratory medicine case reports2019
Bilateral spontaneous pneumothoraces in anaplastic thyroid cancer.
Article in Respiratory medicine case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Recurrent Drug-Induced Pneumothorax Associated With Lenvatinib: A Case Report.Respirology case reports · 2025Article
- Lung cavitation in patients with anaplastic thyroid cancer treated with lenvatinib.Gland surgery · 2022Article
- Pneumothorax during lenvatinib treatment for hepatocellular carcinoma with lung metastasis.Clinical journal of gastroenterology · 2021Article
- Bilateral pneumothorax in a patient with anaplastic thyroid carcinoma and lung metastasis during lenvatinib therapy: a case report.Gland surgery · 2020Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Spontaneous pneumothorax is rarely associated with cancer. We describe a 73 year old man who presented with recurrent tumor in the right neck, mediastinal lymphadenopathy and bilateral pulmonary nodules after thyroidectomy. He was treated with lenvatinib and presented with bilateral pneumothoraces. Anaplastic thyroid cancer is an aggressive subtype of thyroid cancer that has limited response to cytotoxic chemotherapy and poor prognosis. Recent reports show that targeted therapy with a multiple receptor tyrosine kinase inhibitor, lenvatinib, may have improvement in progression-free survival, but rarely pneumothorax has been reported in those with lung metastases. Various mechanisms have been postulated, but necrosis of pulmonary lesions and/or subpleural micrometastases leading to bilateral pleural defects likely resulted in the development of pneumothoraces for our patient.
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