ArticleCurrent oral health reports2018
Growth Factors and Cell Homing in Dental Tissue Regeneration.
Article in Current oral health reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 53 citations in OpenAlex.
- Cell homing within endodontic hydrogels: A scoping review.The Japanese dental science review · 2026Review
- Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review.International endodontic journal · 2026Article
- Bioactive photo-crosslinkable hydrogel based on decellularized dental pulp matrix for functional pulp regeneration.BMC oral health · 2026Article
- Enamel Matrix Derivative in Dental Pulp Regeneration: Biological Basis, Mechanistic Insights, and Translational Considerations.Stem cells international · 2026Review
- Next-generation polymeric nanoparticles for regenerative endodontics: engineering the pulp microenvironment beyond antimicrobial therapy.Frontiers in dental medicine · 2026Review
- Regenerative Dentistry: Applications of Bioactive Materials in Dentin-Pulp Complex.Advances in experimental medicine and biology · 2026Review
- Surgical Management of a Large Radicular Cyst in a Maxillary Incisor Following Failed Regenerative Endodontics and Apical Plug in an Adolescent: A Case Report.Case reports in dentistry · 2026Article
- Effect of Chitosan and bioactive glass nanomaterials as intracanal medicaments on TGF-β1 release from intraradicular dentin.BMC oral health · 2025Article
- Unlocking the Potential of Cellular Guidance in Endodontics: Advancing the Process of Pulp Regeneration and Beyond.Cureus · 2024Review
- Epigenetic therapeutics in dental pulp treatment: Hopes, challenges and concerns for the development of next-generation biomaterials.Bioactive materials · 2023Article
- Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products.Bioengineering (Basel, Switzerland) · 2022Review
- Review
- Cells and material-based strategies for regenerative endodontics.Bioactive materials · 2022Review
- Biomaterial scaffolds for clinical procedures in endodontic regeneration.Bioactive materials · 2022Article
- Regenerative Endodontics Success Factors and their Overall Effectiveness: An Umbrella Review.Iranian endodontic journal · 2022Review
- Fabrication of Vascularized DPSC Constructs for Efficient Pulp Regeneration.Journal of dental research · 2021Article
- Oral Cavity as a Source of Mesenchymal Stem Cells Useful for Regenerative Medicine in Dentistry.Biomedicines · 2021Review
- Leveraging Advancements in Tissue Engineering for Bioprinting Dental Tissues.Bioprinting (Amsterdam, Netherlands) · 2021Article
- Endodontic regeneration: hard shell, soft core.Odontology · 2021Review
- Efficacy of Photobiomodulation and Vitamin D on Odontogenic Activity of Human Dental Pulp Stem Cells.Journal of lasers in medical sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
purpose of reviewTo summarize current views on the role and therapeutic potential of growth factors (GFs) within endodontic cell homing. RECENT
findingsCell homing/revitalization techniques aim to regenerate dentin and pulp using endogenous cells. Clinically, revitalization has successfully created new vital tissue in necrotic permanent teeth with an open apex; however, there is no evidence of new odontoblasts, pulp tissue, or predictable extension in root length. Although the response is reparative rather than regenerative, exciting opportunities to improve these biologically-based strategies remain by (1) efficiently sequestering dentin-matrix-components (DMCs) using irrigants and dental materials (2) designing next-generation GF-releasing scaffold materials and (3) utilizing other sources of GF such as cells and plasma-rich plasma and plasma-rich fibrin. SUMMARY: GFs can promote reparative-dentinogenesis and pulp-like tissue formation. The future development and clinical approval of GF-functionalized-scaffolds is a priority; however, current focus should be to harness DMCs and target the interaction of stem cells and GFs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.