ArticleCureus2018
The Goodness-of-fit of the Fractal Dimension as a Diagnostic Factor in Breast Cancer.
Article in Cureus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Interpretable machine learning classification of cedar and cypress pollen on routine Durham slides for environmental exposure assessment.Frontiers in allergy · 2026Article
- KineticEJNMMI physics · 2024Article
- The diagnostic likelihood ratio function and modified test for trend: Identifying, evaluating, and validating nontraditional biomarkers in case-control studies.Statistics in medicine · 2023Article
- Article
- Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model.Insights into imaging · 2023Article
- Fractal dimension: analyzing its potential as a neuroimaging biomarker for brain tumor diagnosis using machine learning.Frontiers in physiology · 2023Article
- The Fractal Viewpoint of Tumors and Nanoparticles.Current medicinal chemistry · 2023Review
- Fractal dimension analysis as an easy computational approach to improve breast cancer histopathological diagnosis.Applied microscopy · 2021Article
- BrainFD: Measuring the Intracranial Brain Volume With Fractal Dimension.Frontiers in aging neuroscience · 2021Article
- Computational image analysis reveals the structural complexity of Toxoplasma gondii tissue cysts.PloS one · 2020Article
- Perspective of nuclear fractal dimension in diagnosis and prognosis of oral squamous cell carcinoma.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A large number of studies have found that the fractal dimension increases with the progression towards pathological or more pathological states, but there are also studies that have demonstrated the opposite relationship. In this study, we calculate the nuclear box-counting fractal dimension of 109 malignant, 113 benign, and 80 normal isolated breast cells in order to investigate its possible diagnostic importance. We computed the fractal dimension and its goodness-of-fit (i.e., the r-squared value that describes how well the regression line fits the set of the measurements) for two different sets of box size lengths. The statistical analysis did not confirm an important diagnostic potential of the nuclear fractal dimension of isolated breast cells. However, the goodness-of-fit did display a diagnostic potential. The r-squared value may be able to serve as a complementary diagnostic parameter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.