Evidence map›Paper›PMID 30705723›Full record

ArticleWorld journal of hepatology2019

High prevalence of occult hepatitis C infection in predialysis patients.

Luís Henrique Bezerra Cavalcanti Sette, Edmundo Pessoa de Almeida Lopes, Nathália Campello Guedes Dos Anjos, Lucila Maria Valente, Sávio Augusto Vieira de Oliveira, Norma Lucena-Silva

Open access · diamondAbstract read
In one paragraph

Article in World journal of hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Seroprevalence and Spatial Distribution of Hepatitis C Virus in Bahia, Brazil.The American journal of tropical medicine and hygiene · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luís Henrique Bezerra Cavalcanti SetteNephrology-Department of Clinical Medicine, Federal University of Pernambuco, Pernambuco 50670-901, Brazil. luis.sette@ufpe.br.
Edmundo Pessoa de Almeida LopesGastroenterology-Department of Clinical Medicine, Federal University of Pernambuco, Pernambuco 50670-900, Brazil.
Nathália Campello Guedes Dos AnjosNephrology-Department of Clinical Medicine, Federal University of Pernambuco, Pernambuco 50670-901, Brazil.
Lucila Maria ValenteNephrology-Department of Clinical Medicine, Federal University of Pernambuco, Pernambuco 50670-901, Brazil.
Sávio Augusto Vieira de OliveiraLaboratory of Immunogenetics of the Aggeu Magalhães Institute - Fiocruz Pernambuco, Pernambuco 50670-420, Brazil.
Norma Lucena-SilvaLaboratory of Immunogenetics of the Aggeu Magalhães Institute - Fiocruz Pernambuco, Pernambuco 50670-420, Brazil.
Universidade Federal de Pernambuco · BRUniversidade de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOccult hepatitis C virus (HCV) infection (OCI) may be associated with extrahepatic diseases and it is known that the patients with chronic kidney disease (CKD) who are on hemodialysis (HD) present a higher prevalence of this type of infection than the general population, with a worse clinical outcome. However, there are no data in the literature to assess the presence of OCI in patients prior to the initiation of renal replacement therapy (RRT). Therefore, this study aimed to evaluate the occurrence and epidemiological aspects of OCI in patients with Predialysis CKD. We hypothesize that this infection could occur before RRT initiation.

aimTo research the status in predialysis patients when HD patients have high prevalence of OCI.

methodsA cross-sectional study was conducted between 2015 and 2017. Adults with creatinine clearance < 60 mL/min·1.73 m

resultsAmong the 91 total patients included in the study, the prevalence of OCI was 16.5%. Among these 15 total OCI patients, 1 was diagnosed by 14 ultracentrifuged serum results and 14 were diagnosed by peripheral blood mononuclear cell results. Compared to the non-OCI group, the OCI patients presented higher frequency of older age (

conclusionAmong predialysis patients, OCI involved the elderly, patients with CKD of mixed etiology, and patients with previous HBV infection.

Indexed as

Chronic hepatitis CChronic kidney diseaseHemodialysisHepatitis C virus-RNAOccult hepatitis infectionPeripheral blood mononuclear cells

Identifiers

PMID30705723
PMCPMC6354127
OpenAlexW2912141041

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.