Evidence map›Paper›PMID 30705640›Full record

ArticleFrontiers in physiology2018

Milk From Cow Fed With High Forage/Concentrate Ratio Diet: Beneficial Effect on Rat Skeletal Muscle Inflammatory State and Oxidative Stress Through Modulation of Mitochondrial Functions and AMPK Activity.

Giovanna Trinchese, Gina Cavaliere, Eduardo Penna, Chiara De Filippo, Fabiano Cimmino, Angela Catapano, Nadia Musco, Raffaella Tudisco, Pietro Lombardi, Federico Infascelli and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

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  11. Mechanism of Obesity-Related Lipotoxicity and Clinical Perspective.Advances in experimental medicine and biology · 2024
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Giovanna TrincheseDepartment of Biology, University of Naples Federico II, Naples, Italy.
Gina CavaliereDepartment of Biology, University of Naples Federico II, Naples, Italy.
Eduardo PennaDepartment of Biology, University of Naples Federico II, Naples, Italy.
Chiara De FilippoDepartment of Biology, University of Naples Federico II, Naples, Italy.
Fabiano CimminoDepartment of Biology, University of Naples Federico II, Naples, Italy.
Angela CatapanoDepartment of Biology, University of Naples Federico II, Naples, Italy.
Nadia MuscoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Raffaella TudiscoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Pietro LombardiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Federico InfascelliDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Giovanni MessinaDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Laura MureddaDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Sebastiano BanniDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Marcellino MondaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Marianna CrispinoDepartment of Biology, University of Naples Federico II, Naples, Italy.
Maria Pina MollicaDepartment of Biology, University of Naples Federico II, Naples, Italy.
University of Naples Federico II · ITUniversity of Cagliari · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Milk and dairy products are relevant components of daily diet and are part of dietary recommendation in many countries due to their content of key nutrients. However, the relatively high content of saturated fat of the milk and its extensive usage for every age group raises concerns about its potential negative health effects. Therefore, in the last years, several researchers dedicated their attention to milk production and quality. Milk fatty acids profile depend on cow feeding and in particular on the type of forage and concentrate and forage/concentrate ratio. It was demonstrated that feeding dairy cows with a 70/30 forage/concentrate ratio yields milk with a low ω6:ω3 ratio and high CLA levels. In this work, we demonstrated that the supplementation of rats diet with this high forage milk (HFM) results, in the skeletal muscle of these animals, in a reduced lipid content and inflammation levels, and an improved mitochondrial lipid oxidation, and redox status through modulation of AMPK activity.

Indexed as

AMPK activationhigh forage/concentrate ratioinflammationmilkmitochondrial functionsoxidative stressskeletal muscle

Identifiers

PMID30705640
PMCPMC6344429
OpenAlexW2910087763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.