Evidence map›Paper›PMID 30705628›Full record

ArticleFrontiers in aging neuroscience2018

The Neuroprotector Benzothiazepine CGP37157 Extends Lifespan in

Paloma García-Casas, Jessica Arias-Del-Val, Pilar Alvarez-Illera, Aneta Wojnicz, Cristobal de Los Ríos, Rosalba I Fonteriz, Mayte Montero, Javier Alvarez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Rescue of a Rotenone Model of Parkinson's Disease inInternational journal of molecular sciences · 2025
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  6. The Mitochondrial NaFrontiers in pharmacology · 2021
    Article
  7. The Role of CaCells · 2020
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Paloma García-CasasDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, Institute of Biology and Molecular Genetics (IBGM), University of Valladolid and CSIC, Valladolid, Spain.
Jessica Arias-Del-ValDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, Institute of Biology and Molecular Genetics (IBGM), University of Valladolid and CSIC, Valladolid, Spain.
Pilar Alvarez-IlleraDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, Institute of Biology and Molecular Genetics (IBGM), University of Valladolid and CSIC, Valladolid, Spain.
Aneta WojniczDepartment of Clinical Pharmacology, Instituto Teófilo Hernando, Instituto de Investigación Sanitaria la Princesa (IP), Hospital Universitario de la Princesa, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Cristobal de Los RíosDepartment of Clinical Pharmacology, Instituto Teófilo Hernando, Instituto de Investigación Sanitaria la Princesa (IP), Hospital Universitario de la Princesa, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Rosalba I FonterizDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, Institute of Biology and Molecular Genetics (IBGM), University of Valladolid and CSIC, Valladolid, Spain.
Mayte MonteroDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, Institute of Biology and Molecular Genetics (IBGM), University of Valladolid and CSIC, Valladolid, Spain.
Javier AlvarezDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, Institute of Biology and Molecular Genetics (IBGM), University of Valladolid and CSIC, Valladolid, Spain.
Instituto de Biomedicina y Genética Molecular de Valladolid · ESUniversidad de Valladolid · ESHospital Universitario de La Princesa · ESUniversidad Autónoma de Madrid · ES

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

The benzothiazepine CGP37157 has shown neuroprotective effects in several

Indexed as

agingCa2+ signalingC. elegansCGP37157lifespanmitochondriaNa+/Ca2+ exchangerneuroprotection

Identifiers

PMID30705628
PMCPMC6344432
OpenAlexW2909308427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.