Evidence map›Paper›PMID 30705567›Full record

ArticleThe Saudi dental journal2019

Differential expression of salivary S100A7 in oral submucous fibrosis.

Muhammad Arsalan Raffat, Naila Irum Hadi, Mervyn Hosein, Adnan Mustafa Zubairi, Sana Ikram, Zohaib Akram

Open access · hybridAbstract read
In one paragraph

Article in The Saudi dental journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Muhammad Arsalan RaffatDepartment of Oral and Maxillofacial Pathology, Ziauddin College of Dentistry, Ziauddin University, 75600 Karachi, Pakistan.
Naila Irum HadiDepartment of Pathology, Islamabad Medical & Dental College, 45400 Islamabad, Pakistan.
Mervyn HoseinZiauddin College of Dentistry, Ziauddin University, 75600 Karachi, Pakistan.
Adnan Mustafa ZubairiDepartment of Chemical Pathology, Ziauddin University Hospital, 75600 Karachi, Pakistan.
Sana IkramDepartment of Oral Biology, Ziauddin College of Dentistry, Ziauddin University, 75600 Karachi, Pakistan.
Zohaib AkramDepartment of Periodontology, Faculty of Dentistry, Ziauddin University, 75600 Karachi, Pakistan.
Ziauddin University · PKKarachi Medical and Dental College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the expression of salivary S100A7 levels among patients with oral submucous fibrosis (OSF) and healthy controls.

methodA total number of 60 participants were included in the study (30 OSF cases and 30 healthy controls). Demographic data was collected using a structured baseline questionnaire. Salivary S100A7 levels were quantified using enzyme-linked immunosorbent assay. Data was analyzed using Student

resultsThe mean value of salivary S100A7 for OSF group was 0.275 ng/ml, whereas mean value of salivary S100A7 for healthy controls was 0.195 ng/ml. Student

conclusionOSF presented higher levels of salivary S100A7 levels as compared with healthy individuals and may be used as surrogate measure to identify subjects at risk for OSF.

Indexed as

HRP, horseradish peroxidaseNF-κB, nuclear factor kappa-light-chain-enhancer of activated B cellsOral submucous fibrosisOSCC, oral squamous cell carcinomaOSF, oral submucous fibrosisPsoriasin, S100A7RAGEs, receptors of advanced glycated end productsROS, reactive oxygen speciesS100A7 proteinSalivaSPSS, Statistical Package for the Social SciencesTMB, tetramethylbenzidineUWS, unstimulated whole saliva

Identifiers

PMID30705567
PMCPMC6349954
OpenAlexW2893885808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.