ArticleScientific reports2019
Mapping the Surface Microbiome and Metabolome of Brown Seaweed Fucus vesiculosus by Amplicon Sequencing, Integrated Metabolomics and Imaging Techniques.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
- Article
- Integrated holobiont responses of the Antarctic brown seaweedISME communications · 2026Article
- A Practical Comparison of Short- and Long-Read Metabarcoding Sequencing: Challenges and Solutions for Plastid Read Removal and Microbial Community Exploration of Seaweed Samples.Molecular ecology resources · 2025Article
- Antimicrobial activity of some bacteria isolated from marine sponge in Neom region, Saudi Arabia.BMC microbiology · 2025Article
- Diversity of the surface microbiome of canopy-forming brown macroalgae (Fucales) in the northern Adriatic.Microbiology spectrum · 2025Article
- Multi-omics analysis of the correlation between surface microbiome and metabolome in Saccharina latissima (Laminariales, Phaeophyceae).FEMS microbiology ecology · 2025Article
- Microbiome in cancer metastasis: biological insights and emerging spatial omics methods.Frontiers in cellular and infection microbiology · 2025Review
- Community dynamics and metagenomic analyses reveal Bacteroidota's role in widespread enzymatic Fucus vesiculosus cell wall degradation.Scientific reports · 2024Article
- Functional guilds and drivers of diversity in seaweed-associated bacteria.FEMS microbes · 2024Article
- Metabolomics and Microbiomics Insights into Differential Surface Fouling of Three Macroalgal Species ofMarine drugs · 2023Article
- Nanomechanical Signatures in Glioma Cells Depend on CD44 Distribution in IDH1 Wild-Type but Not in IDH1R132H Mutant Early-Passage Cultures.International journal of molecular sciences · 2023Article
- Alternative approaches to identify core bacteria in Fucus distichus microbiome and assess their distribution and host-specificity.Environmental microbiome · 2022Article
- Advances in experimental and computational methodologies for the study of microbial-surface interactions at different omics levels.Frontiers in microbiology · 2022Review
- TheFrontiers in microbiology · 2022Article
- Recent advances in tools to map the microbiome.Current opinion in biomedical engineering · 2021Article
- The Microbiome of the Reef MacroalgaMicroorganisms · 2021Article
- A new glance at the chemosphere of macroalgal-bacterial interactions: In situ profiling of metabolites in symbiosis by mass spectrometry.Beilstein journal of organic chemistry · 2021Article
- Comparative Microbiome and Metabolome Analyses of the Marine TunicateMicroorganisms · 2020Article
- Culture-Dependent Microbiome of theMicroorganisms · 2020Article
- Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The brown alga Fucus vesiculosus is a keystone marine species, which is subject to heavy surface colonisation. This study was designed to analyse the surface epibiome of F. vesiculosus in conjunction with the composition and spatial distribution of its surface metabolome. The amplicon sequencing, SEM and CARD-FISH imaging studies showed Alphaproteobacteria to predominate the epibiotic bacteria. Fungi of the class Eurotiomycetes were visualised for the first time on an algal surface. An untargeted metabolomics approach using molecular networks, in silico prediction and manual dereplication showed the differential metabolome of the surface and the whole tissue extracts. In total, 50 compounds were putatively dereplicated by UPLC-MS/MS, 37 of which were previously reported from both seaweeds and microorganisms. Untargeted spatial metabolomics by DESI-Imaging MS identified the specific localisation and distribution of various primary and secondary metabolites on surface imprints and in algal cross sections. The UPLC-MS, DESI-IMS and NMR analyses failed to confirm the presence of any surface-associated metabolite, except for mannitol, which were previously reported from F. vesiculosus. This is the first study analysing the seaweed surface microbiome in conjunction with untargeted surface metabolomics and spatial metabolomics approaches.
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