Evidence map›Paper›PMID 30705399›Full record

ArticlePediatric research2019

Accuracy of preterm infant weight gain velocity calculations vary depending on method used and infant age at time of measurement.

Tanis R Fenton, Ian J Griffin, Angela Hoyos, Sharon Groh-Wargo, Diane Anderson, Richard A Ehrenkranz, Thibault Senterre

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03064022 (Preterm Infant Multicentre Growth Study), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03064022 completednot on this map

Preterm Infant Multicentre Growth Study

TypeobservationalSponsorUniversity of CalgaryRan2009 to 2019Enrolled1,275ConditionsPreterm InfantArmsGrowth
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Higher versus lower protein intake in formula-fed low birth weight infants.The Cochrane database of systematic reviews · 2020
    Pooled it
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  8. Review
  9. Observational
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  14. Morbidity and mortality in neonates with Down Syndrome based on gestational age.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
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  16. Article
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  20. "Extrauterine growth restriction" and "postnatal growth failure" are misnomers for preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanis R FentonNutrition Services, Alberta Health Services, Community Health Sciences, Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada. TFenton@ucalgary.ca.
Ian J GriffinBiomedical Research Institute of New Jersey & Mid-Atlantic Neonatal Associates, Morristown, NJ, USA.
Angela HoyosClínica del Country, Universidad el Bosque, Bogotá, Colombia.
Sharon Groh-WargoCase Western Reserve University School of Medicine, Cleveland, OH, USA.
Diane AndersonBaylor College of Medicine, Houston, TX, USA.
Richard A EhrenkranzYale School of Medicine, New Haven, CT, USA.
Thibault SenterreCHU de Liege, CHR de la Citadelle, University of Liege, Liege, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined preterm infants' weight gain velocity (WGV) to determine how much calculation methods influences actual WGV during the first 28 days of life.

methodsWGV methods (Average 2-point, Exponential 2-point, Early 1-point, and Daily) were calculated weekly and for various start times (birth, nadir, regain, day 3 and day 7) to 28 days of age for 103 preterm < 1500 gram infants, with daily weights.

resultsRange of WGV estimates decreased 10-22 g/kg/day to 15.5-15.8 g/kg/day when the Early 1-point method and the postnatal weight loss phase were excluded. WGV were lower when the postnatal weight loss was included and higher using the early method. WGV calculations beginning at day 7 did not differ from calculations beginning at the nadir.

conclusionsVariations in WGV calculations were large enough to create difficulties for comparing results between studies and translating research to practice. We recommend that the postnatal weight loss phase be excluded from WGV calculations and clinical studies report weight nadir and weights at day 7 and 28 to allow adequate comparison and translation of findings in clinical practice. The Average2pt method may be easier to calculate at bedside, so we recommend it be used in clinical settings and research summaries. The Early1pt method should not be used to summarize WGV for research.

Indexed as

Body WeightWeight GainAnthropometryData CollectionFemaleHumansInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureMaleReference ValuesReproducibility of ResultsWeight Loss

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.