Evidence map›Paper›PMID 30705350›Full record

ArticleScientific reports2019

Sputum Proteomics Reveals a Shift in Vitamin D-binding Protein and Antimicrobial Protein Axis in Tuberculosis Patients.

Subasa C Bishwal, Mrinal K Das, Vinod K Badireddy, Deepti Dabral, Aleena Das, Alok R Mahapatra, Sukanya Sahu, Dipankar Malakar, I Ibungo Singh, Himanghsu Mazumdar and 21 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Perspectives for systems biology in the management of tuberculosis.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 8 institutions in 1 country.

Subasa C BishwalTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Mrinal K DasTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Vinod K BadireddyTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Deepti DabralTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Aleena DasTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.ORCID 0000-0002-2101-9056
Alok R MahapatraSchool of Life Sciences, Sambalpur University, JyotiVihar, Sambalpur, India.
Sukanya SahuTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Dipankar MalakarSciex, 121 UdyogVihar, Gurgaon, Haryana, India.
I Ibungo SinghDepartment of Respiratory Medicine, Regional Institute of Medical Sciences, Imphal, India.
Himanghsu MazumdarDepartment of Microbiology, Assam Medical College and Hospital, Dibrugarh, India.
Saurav J PatgiriDepartment of Microbiology, Assam Medical College and Hospital, Dibrugarh, India.
Trinayan DekaDepartment of Microbiology, Assam Medical College and Hospital, Dibrugarh, India.
Wetetsho KapfoHealthcare Laboratory and Research Centre, Naga Hospital Authority Kohima, Nagaland, India.
Kevideme LiegiseHealthcare Laboratory and Research Centre, Naga Hospital Authority Kohima, Nagaland, India.
Rukuwe-U KupaHealthcare Laboratory and Research Centre, Naga Hospital Authority Kohima, Nagaland, India.
Sanjita DebnathDepartment of Respiratory Medicine, Agartala Government Medical College, Agartala, India.
Rajesh BhowmikDepartment of Respiratory Medicine, Agartala Government Medical College, Agartala, India.
Rahul DebnathDepartment of Respiratory Medicine, Agartala Government Medical College, Agartala, India.
Rajendra K BeheraSchool of Life Sciences, Sambalpur University, JyotiVihar, Sambalpur, India.
Manoj G PillaiSciex, 121 UdyogVihar, Gurgaon, Haryana, India.
Pranjal DeuriDepartment of Microbiology, Assam Medical College and Hospital, Dibrugarh, India.
Reema NathDepartment of Microbiology, Assam Medical College and Hospital, Dibrugarh, India.
K Pewezo KhaloDepartment of Microbiology, Naga Hospital Authority Kohima, Nagaland, India.
W Asoka SingDepartment of Respiratory Medicine, Regional Institute of Medical Sciences, Imphal, India.
Bhaswati PanditNational Institute of Biomedical Genomics, Kalyani, West Bengal, India.
Anjan DasDepartment of Respiratory Medicine, Agartala Government Medical College, Agartala, India.
Sibabrata BhattacharyaDepartment of Microbiology, Agartala Government Medical College, Agartala, India.
Digambar BeheraDepartment of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Lahari SaikiaDepartment of Microbiology, Assam Medical College and Hospital, Dibrugarh, India.
Vinotsole KhamoHealthcare Laboratory and Research Centre, Naga Hospital Authority Kohima, Nagaland, India.
Ranjan K NandaTranslational Health Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India. ranjan@icgeb.res.in.ORCID 0000-0002-2163-4411
International Centre for Genetic Engineering and Biotechnology · INAssam Medical College · INNagaland University · INAgartala Government Medical College · INSambalpur University · INRegional Institute of Medical Sciences · INNational Institute of Biomedical Genomics · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Existing understanding of molecular composition of sputum and its role in tuberculosis patients is variously limited to its diagnostic potential. We sought to identify infection induced sputum proteome alteration in active/non tuberculosis patients (A/NTB) and their role in altered lung patho-physiology. Out of the study population (n = 118), sputum proteins isolated from discovery set samples (n = 20) was used for an 8-plex isobaric tag for relative and absolute concentration analysis. A minimum set of protein with at least log

Indexed as

ProteomicsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsFemaleHumansMaleMiddle AgedProteomeReproducibility of ResultsSputumTuberculosisVitamin D-Binding ProteinYoung AdultAnti-Bacterial AgentsProteomeVitamin D-Binding Protein

Identifiers

PMID30705350
PMCPMC6355791
OpenAlexW2924129057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.