ArticleNature communications2019
Reductions in prefrontal activation predict off-topic utterances during speech production.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Reduced linguistic coherence in psychosis defies semantic similarity accounts and relates to altered large-scale cortical hierarchy.Scientific reports · 2026Article
- Fragmentation and multithreading of experience in the default-mode network.Nature communications · 2025Article
- Neural representations of noncentral events during narrative encoding predict subsequent story ending originality.Science advances · 2025Article
- Mapping the task-general and task-specific neural correlates of speech production: Meta-analysis and fMRI direct comparisons of category fluency and picture naming.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Article
- Speech decoding using cortical and subcortical electrophysiological signals.Frontiers in neuroscience · 2024Article
- The left posterior angular gyrus is engaged by autobiographical recall not object-semantics, or event-semantics: Evidence from contrastive propositional speech production.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Similar neural networks respond to coherence during comprehension and production of discourse.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The cognitive and neural underpinnings of discourse coherence in post-stroke aphasia.Brain communications · 2022Article
- Stimulus-independent neural coding of event semantics: Evidence from cross-sentence fMRI decoding.NeuroImage · 2021Article
- Revealing the neural networks that extract conceptual gestalts from continuously evolving or changing semantic contexts.NeuroImage · 2020Article
- Barking up the right tree: Univariate and multivariate fMRI analyses of homonym comprehension.NeuroImage · 2020Article
- Going off the rails: Impaired coherence in the speech of patients with semantic control deficits.Neuropsychologia · 2020Article
- The pressure to communicate efficiently continues to shape language use later in life.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
The ability to speak coherently is essential for effective communication but declines with age: older people more frequently produce tangential, off-topic speech. Little is known, however, about the neural systems that support coherence in speech production. Here, fMRI was used to investigate extended speech production in healthy older adults. Computational linguistic analyses were used to quantify the coherence of utterances produced in the scanner, allowing identification of the neural correlates of coherence for the first time. Highly coherent speech production was associated with increased activity in bilateral inferior prefrontal cortex (BA45), an area implicated in selection of task-relevant knowledge from semantic memory, and in bilateral rostrolateral prefrontal cortex (BA10), implicated more generally in planning of complex goal-directed behaviours. These findings demonstrate that neural activity during spontaneous speech production can be predicted from formal analysis of speech content, and that multiple prefrontal systems contribute to coherence in speech.
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