Evidence map›Paper›PMID 30705071›Full record

ArticleAJNR. American journal of neuroradiology2019

Neuroimaging-Based Classification Algorithm for Predicting 1p/19q-Codeletion Status in

P P Batchala, T J E Muttikkal, J H Donahue, J T Patrie, D Schiff, C E Fadul, E K Mrachek, M-B Lopes, R Jain, S H Patel

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. An Expanded T2-FLAIR Mismatch Phenotype in IDH-Mutant Astrocytomas.Journal of magnetic resonance imaging : JMRI · 2026
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  16. Pediatric-type diffuse low-grade glioma with T2-FLAIR mismatch sign: a case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  17. Identification of T2W hypointense ring as a novel noninvasive indicator for glioma grade and IDH genotype.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  18. Article
  19. Article
  20. Advances in diffuse glial tumors diagnosis.Arquivos de neuro-psiquiatria · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

P P BatchalaFrom the Department of Radiology and Medical Imaging (P.P.B., T.J.E.M., J.H.D., S.H.P.).ORCID 0000-0002-3744-7012
T J E MuttikkalFrom the Department of Radiology and Medical Imaging (P.P.B., T.J.E.M., J.H.D., S.H.P.).ORCID 0000-0002-3393-2555
J H DonahueFrom the Department of Radiology and Medical Imaging (P.P.B., T.J.E.M., J.H.D., S.H.P.).ORCID 0000-0002-4964-4726
J T PatrieDepartment of Public Health Sciences (J.T.P.).ORCID 0000-0001-7392-830X
D SchiffDivision of Neuro-Oncology (D.S., C.E.F.).ORCID 0000-0002-1896-2502
C E FadulDivision of Neuro-Oncology (D.S., C.E.F.).ORCID 0000-0001-7459-7661
E K MrachekDepartment of Pathology (E.K.M., M.-B.L.), Divisions of Neuropathology and Molecular Diagnostics, University of Virginia Health System, Charlottesville, Virginia.ORCID 0000-0003-1184-3567
M-B LopesDepartment of Pathology (E.K.M., M.-B.L.), Divisions of Neuropathology and Molecular Diagnostics, University of Virginia Health System, Charlottesville, Virginia.ORCID 0000-0001-8661-6727
R JainDepartments of Radiology (R.J.).ORCID 0000-0002-4879-0457
S H PatelFrom the Department of Radiology and Medical Imaging (P.P.B., T.J.E.M., J.H.D., S.H.P.) shp4k@virginia.edu.ORCID 0000-0002-9739-4362
Hesco (United States) · USCenter for Neuro-Oncology · USUniversity of Virginia Health System · USFaculty of Public Health · GBResearch Institute of Radiology · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMATERIALS AND

methodsOne hundred two

resultsTraining dataset analysis produced a 2-step classification algorithm with 86.3% codeletion prediction accuracy, based on the following: 1) the presence of the T2-FLAIR mismatch sign, which was 100% predictive of noncodeleted lower grade gliomas, (

conclusionsWe have validated a classification algorithm based on simple, reproducible neuroimaging metrics and patient age that demonstrates a moderate prediction accuracy of 1p/19q-codeletion status among

Indexed as

AlgorithmsAdultAgedAstrocytomaBrain NeoplasmsChromosomes, Human, Pair 1Cohort StudiesFemaleGliomaHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMaleMiddle AgedMutationNeuroimagingIsocitrate Dehydrogenase

Identifiers

PMID30705071
PMCPMC7028667
OpenAlexW2914998138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.