Evidence map›Paper›PMID 30704978›Full record

ArticleCellular and molecular gastroenterology and hepatology2019

Genome-Wide Epigenetic and Transcriptomic Characterization of Human-Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids.

Judith Kraiczy, Alexander D B Ross, Jessica L Forbester, Gordon Dougan, Ludovic Vallier, Matthias Zilbauer

Abstract readLetter
In one paragraph

Article in Cellular and molecular gastroenterology and hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Multiscale Construction, Evaluation, and Application of Organoids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Judith KraiczyDepartment of Pediatrics, University of Cambridge, Cambridge, United Kingdom.
Alexander D B RossDepartment of Pediatrics, University of Cambridge, Cambridge, United Kingdom; Wellcome Trust-MRC Cambridge Stem Cell Institute, Anne McLaren Laboratory and Department of Surgery, University of Cambridge, United Kingdom.
Jessica L ForbesterWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; Institute of Infection and Immunity, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.
Gordon DouganWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Ludovic VallierWellcome Trust-MRC Cambridge Stem Cell Institute, Anne McLaren Laboratory and Department of Surgery, University of Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Matthias ZilbauerDepartment of Pediatrics, University of Cambridge, Cambridge, United Kingdom; Department of Pediatric Gastroenterology, Hepatology and Nutrition, Addenbrooke's Hospital, Cambridge, United Kingdom; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, United Kingdom. Electronic address: mz304@medschl.cam.ac.uk.

Funding

Medical Research Council MC_PC_12009National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/N001540/1Wellcome TrustWellcome Trust 100138/B/12/ZWellcome Trust 206194
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epigenesis, GeneticGenome, HumanEpithelial CellsHumansInduced Pluripotent Stem CellsIntestinal MucosaOrganoidsTranscriptome

Identifiers

PMID30704978
PMCPMC6354438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.