Evidence map›Paper›PMID 30704976›Full record

ReviewAutonomic neuroscience : basic & clinical2019

Autonomic nerves and circadian control of renal function.

Bryan K Becker, Dingguo Zhang, Reham Soliman, David M Pollock

Abstract readReview
In one paragraph

Review in Autonomic neuroscience : basic & clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Circadian Control of Sodium and Blood Pressure Regulation.American journal of hypertension · 2021
    Review
  5. Review
  6. The Circadian Clock and Viral Infections.Journal of biological rhythms · 2021
    Review
  7. Impact of anesthesia, sex, and circadian cycle on renal afferent nerve sensitivity.American journal of physiology. Heart and circulatory physiology · 2021
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bryan K BeckerSection of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, United States of America.
Dingguo ZhangSection of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, United States of America.
Reham SolimanSection of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, United States of America.
David M PollockSection of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, United States of America. Electronic address: davidpollock@uabmc.edu.
University of Alabama at Birmingham · US

Funding

Vascular and renal responses to stressP01HL069999 · NHLBI · MEDICAL COLLEGE OF GEORGIA (MCG) · PI HARSHFIELD, GREGORY ALAN · 2002 to 2018
$31.1M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Research Supplement to Promote DiversityP01HL136267 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI POLLOCK, DAVID M · 2017 to 2021
$11.9M
MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
NHLBI NIH HHS P01 HL069999NHLBI NIH HHS P01 HL136267NHLBI NIH HHS T32 HL007457NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Cardiovascular and renal physiology follow strong circadian rhythms. For instance, renal excretion of solutes and water is higher during the active period compared to the inactive period, and blood pressure peaks early in the beginning of the active period of both diurnal and nocturnal animals. The control of these rhythms is largely dependent on the expression of clock genes both in the central nervous system and within peripheral organs themselves. Although it is understood that the central and peripheral clocks interact and communicate, few studies have explored the specific mechanism by which various organ systems within the body are coordinated to control physiological processes. The renal sympathetic nervous innervation has long been known to have profound effects on renal function, and because the sympathetic nervous system follows strong circadian rhythms, it is likely that autonomic control of the kidney plays an integral role in modulating renal circadian function. This review highlights studies that provide insight into this interaction, discusses areas lacking clarity, and suggests the potential for future work to explore the role of renal autonomics in areas such as blood pressure control and chronic kidney disease.

Indexed as

AnimalsBlood PressureCircadian RhythmCircadian Rhythm Signaling Peptides and ProteinsHumansHypertensionKidneyRenal Insufficiency, ChronicSympathetic Nervous SystemCircadian Rhythm Signaling Peptides and ProteinsBlood pressureClock genesKidney functionSympathetic nervous system

Identifiers

PMID30704976
PMCPMC6415626
OpenAlexW2910105868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.