Evidence map›Paper›PMID 30704536›Full record

ArticleLipids in health and disease2019

The relationship between red blood cell distribution width and metabolic syndrome in elderly Chinese: a cross-sectional study.

Ziyu Yan, Yaguang Fan, Zhaowei Meng, Chao Huang, Ming Liu, Qing Zhang, Kun Song, Qiyu Jia

Abstract read
In one paragraph

Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziyu YanDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, 300052, Tianjin, People's Republic of China.
Yaguang FanDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, 300052, Tianjin, People's Republic of China.
Zhaowei MengDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, 300052, Tianjin, People's Republic of China. jamesmencius@163.com.
Chao HuangUniversity of Hull, Allam Medical Building, Cottingham Road, Hull, HU6 7RX, UK.
Ming LiuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Qing ZhangDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Kun SongDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Qiyu JiaDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMetabolic syndrome (MS) is a group of risk factors which includes hypertension, hyperglycemia, abnormal cholesterol levels, and obesity. Red blood cell distribution width (RDW) is a parameter that reflects the heterogeneity of erythrocyte volume. But the relationship between MS and RDW is intricate and remains poorly understood. We hypothesized that high RDW was associated with MS via inflammation. Our study aimed to investigate the association between RDW and MS in Chinese elderly large cohort. If RDW had a strong correlation with MS, RDW could become a predictor of MS?

methodsWe recruited 10,887 ostensibly healthy participants aged from 60 to 93 (5795 male, 5092 female). Associations between RDW and other variables were assessed by Pearson correlation. Crude and adjusted odds ratio for MS with 95% confidence intervals was calculated by binary logistic regression models.

resultsIn elderly Chinese, RDW was significantly higher in males than in females. The prevalence of both men and women decreased with the rise of RDW. For both sexes, RDW demonstrated positive correlations with age, systolic blood pressure (0.070 in males,0.058 in females), high density lipoprotein(0.027in males,0.064 in females), negative correlations with triglycerides (- 0.120 in males,-0.074 in females) and fasting glucose (- 0.048 in males,-0.016 in females). Notably, we detected the associated reduced risks at the the third and fourth quartile of RDW in males. In women, there was no statistical significance.

conclusionWe found the adjusted odds ratios of MS was lower at the third and fourth quartile of RDW in males.

Indexed as

Erythrocyte IndicesAgedAged, 80 and overBlood GlucoseBlood PressureChinaCross-Sectional StudiesFemaleHumansLipoproteins, HDLMaleMetabolic SyndromeMiddle AgedSex FactorsTriglyceridesBlood GlucoseLipoproteins, HDLTriglyceridesAgeGenderMetabolic syndrome (MS)Red blood cell distribution width (RDW)

Identifiers

PMID30704536
PMCPMC6357446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.