Evidence map›Paper›PMID 30704484›Full record

ArticleTheoretical biology & medical modelling2019

Modeling Clostridium difficile in a hospital setting: control and admissions of colonized and symptomatic patients.

Farida Chamchod, Prasit Palittapongarnpim

Abstract read
In one paragraph

Article in Theoretical biology & medical modelling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Farida ChamchodDepartment of Mathematics, Faculty of Science, Mahidol University, Bangkok, Thailand. farida.cha@mahidol.ac.th.
Prasit PalittapongarnpimDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClostridium difficile (C. difficile) infection is an important cause of healthcare-associated diarrhea. Several factors such as admission of colonized patients, levels of serum antibodies in patients, and control strategies may involve in determining the prevalence and the persistence of C. difficile in a hospital unit.

methodsWe develop mathematical models based on deterministic and stochastic frameworks to investigate the effects of control strategies for colonized and symptomatic patients and admissions of colonized and symptomatic patients on the prevalence and the persistence of C. difficile.

resultsOur findings suggest that control strategies and admissions of colonized and symptomatic patients play important roles in determining the prevalence and the persistence of C. difficile. Improving control of C. difficile in colonized and symptomatic patients may generally help reduce the prevalence and the persistence of C. difficile. However, if admission rates of colonized and symptomatic patients are high, the prevalence of C. difficile may remain high in a patient population even though strict control policies are applied.

conclusionControl strategies and admissions of colonized and symptomatic patients are important determinants of the prevalence and the persistence of C. difficile.

Indexed as

HospitalizationHospitalsBasic Reproduction NumberClostridioides difficileClostridium InfectionsHumansModels, TheoreticalPrevalenceStochastic ProcessesAdmission of patientsControl implementationDisruption of the gut floraTransmission of Clostridium difficile

Identifiers

PMID30704484
PMCPMC6357410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.