Evidence map›Paper›PMID 30704107›Full record

ArticleGenes2019

Insights into Catalytic and tRNA Recognition Mechanism of the Dual-Specific tRNA Methyltransferase from

Aiswarya Krishnamohan, Samantha Dodbele, Jane E Jackman

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Fluorescent Dyes for Differential Scanning Fluorimetry of RNA.Chembiochem : a European journal of chemical biology · 2025
    Article
  4. The Landscape of tRNA Modifications in Archaea.bioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Biological roles of RNA mBiomarker research · 2022
    Review
  11. Article
  12. Article
  13. Distinct Modified Nucleosides in tRNAJournal of bacteriology · 2019
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aiswarya KrishnamohanThe Ohio State Biochemistry Program, Center for RNA Biology and Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA. krishnamohan.1@buckeyemail.osu.edu.ORCID 0000-0002-1927-1658
Samantha DodbeleThe Ohio State Biochemistry Program, Center for RNA Biology and Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA. dodbele.1@buckeyemail.osu.edu.
Jane E JackmanThe Ohio State Biochemistry Program, Center for RNA Biology and Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA. jackman.14@osu.edu.ORCID 0000-0001-9291-8852
The Ohio State University · US

Funding

Mechanisms and Biological functions of SPOUT methyltransferasesR01GM130135 · NIGMS · OHIO STATE UNIVERSITY · PI Jane Elizabeth Jackman · 2018 to 2026
$2.3M
Cellular, molecular, and biochemical sciences training grantT32GM086252 · NIGMS · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH, MUSIER-FORSYTH, KARIN M · 2011 to 2020
$2.0M
A Systems Biology Approach for Targeted Drug Discovery for LeishmaniasisR21AI127582 · NIAID · OHIO STATE UNIVERSITY · PI IBBA, MICHAEL, SATOSKAR, ABHAY R · 2017 to 2018
$401k
Typhoon FLA9500 Biomedical ImagerS10OD023582 · OD · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH · 2017 to 2017
$144k
NIAID NIH HHS R21 AI127582NIGMS NIH HHS R01 GM130135NIGMS NIH HHS T32 GM086252NIH HHS S10 OD023582
6 · The paper itself

Abstract

The tRNA methyltransferase Trm10, conserved throughout Eukarya and Archaea, catalyzes N1-methylation of purine residues at position 9 using

Indexed as

Catalytic DomainArchaeal ProteinsProtein BindingRNA, TransferThermococcustRNA MethyltransferasesArchaeal ProteinsRNA, TransfertRNA Methyltransferasesenzyme mechanismTrm10tRNA methylation

Identifiers

PMID30704107
PMCPMC6410153
OpenAlexW2911514394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.