Evidence map›Paper›PMID 30704019›Full record

ReviewViruses2019

Back to the Future for Influenza Preimmunity-Looking Back at Influenza Virus History to Infer the Outcome of Future Infections.

Magen Ellen Francis, Morgan Leslie King, Alyson Ann Kelvin

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 95 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Interim 2025/26 influenza vaccine effectiveness estimates with immuno-epidemiological considerations for A(H3N2) subclade K protection, Canada, January 2026.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Vaccine effectiveness estimates from an early-season influenza A(H3N2) epidemic, including unique genetic diversity with reassortment, Canada, 2022/23.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Magen Ellen FrancisDepartment of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS B3K 6R8, Canada. M.Francis@dal.ca.
Morgan Leslie KingDepartment of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS B3K 6R8, Canada. MorganKing@dal.ca.
Alyson Ann KelvinDepartment of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS B3K 6R8, Canada. akelvin@dal.ca.ORCID 0000-0003-0940-0847
Dalhousie University · CA

Funding

Omics-Based Predictive Modeling of Age-Dependent Outcome to Influenza InfectionU01AI111598 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GHEDIN, ELODIE · 2013 to 2017
$13.3M
NIAID NIH HHS U01 AI111598Nova Scotia Health Research Foundation #1023605Office of Extramural Research, National Institutes of Health 1U01AI11598-01 Subaward no. F8802-16 S
6 · The paper itself

Abstract

The influenza virus-host interaction is a classic arms race. The recurrent and evolving nature of the influenza virus family allows a single host to be infected several times. Locked in co-evolution, recurrent influenza virus infection elicits continual refinement of the host immune system. Here we give historical context of circulating influenza viruses to understand how the individual immune history is mirrored by the history of influenza virus circulation.

Indexed as

AnimalsAntigens, ViralHost Microbial InteractionsHumansImmunity, HerdInfluenza, HumanOrthomyxoviridaeOrthomyxoviridae InfectionsPandemicsVaccinationAntigens, Viralantigenic driftantigenic shiftimmune responseimprintinginfluenza virusoriginal antigenic sinorthomyxoviridaepandemicpreimmunitySpanish influenza

Identifiers

PMID30704019
PMCPMC6410066
OpenAlexW2914727986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.