Evidence map›Paper›PMID 30703573›Full record

ArticleNutrition (Burbank, Los Angeles County, Calif.)2019

Effects of seafood consumption and toenail mercury and selenium levels on cognitive function among American adults: 25 y of follow up.

Xuanxia Mao, Cheng Chen, Pengcheng Xun, Martha Daviglus, Lyn M Steffen, David R Jacobs, Linda Van Horn, Stephen Sidney, Na Zhu, Ka He

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition (Burbank, Los Angeles County, Calif.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Xuanxia MaoDepartment of Clinical Nutrition, School of Medicine, Xin Hua Hospital Affiliated with Shanghai Jiao Tong University, Shanghai, China; Department of Nutrition, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Cheng ChenDepartment of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA.
Pengcheng XunDepartment of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA.
Martha DaviglusDepartment of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Lyn M SteffenDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
David R JacobsDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Linda Van HornDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Stephen SidneyDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Na ZhuIndiana University Health Arnett Hospital, Lafayette, Indiana, USA.
Ka HeDepartment of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA. Electronic address: Kahe@indiana.edu.
Indiana University Bloomington · USUniversity of Minnesota · USIndiana University Health · USKaiser Permanente · USNorthwestern University · USShanghai Jiao Tong University · CNUniversity of Illinois Chicago · US

Funding

Trace mineral levels, the trajectory of cognitive decline and telomere attritionRF1AG056111 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI KAHE, KA · 2017 to 2017
$3.1M
Trace Elements and CVD Risks Factors Among Young AdultsR01HL081572 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAHE, KA · 2006 to 2008
$1.2M
NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029CNHLBI NIH HHS R01 HL081572NIA NIH HHS RF1 AG056111
6 · The paper itself

Abstract

objectivesThe aim of this study was to examine the longitudinal association between seafood and intake of long-chain ω-3 polyunsaturated fatty acids (LCω-3 PUFA) and cognitive function and to explore the possible effect modifications owing to mercury (Hg) and selenium (Se) levels.

methodsParticipants (N = 3231) from the CARDIA (Coronary Artery Risk Development in Young Adults) study underwent baseline examination and were reexamined in eight follow-up visits. Diet was assessed at baseline and in exam years 7 and 20. Toenail Hg and Se were measured at exam year 2. Cognitive function was measured at exam year 25 using three tests: Rey Auditory Verbal Learning Test (RAVLT), Digit Symbol Substitution Test (DSST), and the Stroop test. The general linear regression model was used to examine cumulative average intakes of LCω-3 PUFA and seafood in relation to the cognitive test scores; and to explore the possible effect modifications caused by Hg and Se.

resultsLCω-3 PUFA intake was significantly associated with better performance in the DSST test (quintile 5 versus quintile 1; mean difference = 1.74; 95% confidence interval, 0.19-3.29; P

conclusionThis longitudinal study supported the hypothesis that LCω-3 PUFA or non-fried seafood intake is associated with better cognitive performance in psychomotor speed among US adults, especially those who are overweight or obese.

Indexed as

CognitionEatingFatty Acids, Omega-3FemaleFollow-Up StudiesHumansLinear ModelsLongitudinal StudiesMaleMercuryMiddle AgedNailsNeuropsychological TestsPsychomotor PerformanceSeafoodSeleniumFatty Acids, Omega-3MercurySeleniumCognitive functionHgLCω-3 PUFASeSeafood consumption

Identifiers

PMID30703573
PMCPMC6422693
OpenAlexW2900603015

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.