Evidence map›Paper›PMID 30703401›Full record

ReviewSurvey of ophthalmology

Microperimetry for geographic atrophy secondary to age-related macular degeneration.

Karl G Csaky, Praveen J Patel, Yasir J Sepah, David G Birch, Diana V Do, Michael S Ip, Robyn H Guymer, Chi D Luu, Shamika Gune, Hugh Lin and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Visual Function Assessment in Geographic Atrophy: A Review.Clinical & experimental ophthalmology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Karl G CsakyTexas Retina Associates, Dallas, Texas, USA; Retina Foundation of the Southwest, Dallas, Texas, USA. Electronic address: kcsaky@retinafoundation.org.
Praveen J PatelNIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.
Yasir J SepahByers Eye Institute, Stanford University School of Medicine, Palo Alto, California, USA.
David G BirchRetina Foundation of the Southwest, Dallas, Texas, USA.
Diana V DoByers Eye Institute, Stanford University School of Medicine, Palo Alto, California, USA.
Michael S IpDoheny Eye Institute, Los Angeles, California, USA.
Robyn H GuymerCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital; Department of Surgery (Ophthalmology), University of Melbourne, Victoria, Australia.
Chi D LuuCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital; Department of Surgery (Ophthalmology), University of Melbourne, Victoria, Australia.
Shamika GuneGenentech, Inc., South San Francisco, California, USA.
Hugh LinGenentech, Inc., South San Francisco, California, USA.
Daniela FerraraGenentech, Inc., South San Francisco, California, USA.

Funding

MEASURES OF HUMAN RECEPTOR AND POST RECEPTOR ACTIVITYR01EY009076 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI BIRCH, DAVID G, HOOD, DONALD C. · 1991 to 2021
$8.3M
NEI NIH HHS R01 EY009076
6 · The paper itself

Abstract

Geographic atrophy (GA) is a progressive, advanced form of age-related macular degeneration leading to visual function impairment and irreversible vision loss. Standard clinical tests to evaluate visual function in patients with GA provide poor anatomic-functional correlation, whereas fundus imaging does not assess the visual function deficit. Microperimetry is a psychophysical visual function test that spatially maps retinal sensitivity and allows for identification of correlation of anatomic features with visual function. In this review, we present an overview of mesopic microperimetry for GA, including commercially available microperimetry devices, strategies to capture a mesopic microperimetry test, and strategies to assess and interpret microperimetry data in patients with GA. We demonstrate the importance of microperimetry data for assessing GA progression and for evaluating visual function loss through anatomic-functional correlations. Although valuable, current microperimetry tests require an extensive time commitment from the patient and examiner, and the development of faster, more reproducible and accessible methods is important to enable broader use of microperimetry in both clinical and research settings.

Indexed as

Diagnostic Techniques, OphthalmologicalGeographic AtrophyHumansMacular DegenerationVisual FieldsVisual Field Testsage-related macular degenerationanatomic-functional correlationgeographic atrophymicroperimetryretinal sensitivityvisual function

Identifiers

PMID30703401
PMCPMC6532786

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.