Evidence map›Paper›PMID 30703251›Full record

ArticleJournal of the American Geriatrics Society2019

Differences in National Diabetes Treatment Patterns and Trends between Older and Younger Adults.

Scott J Pilla, Jodi B Segal, G Caleb Alexander, Cynthia M Boyd, Nisa M Maruthur

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. A National Physician Survey Examining Switching From Sulfonylureas or Insulin to Newer Diabetes Medications.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  4. Crossing the deintensification chasm for older adults with diabetes.Journal of the American Geriatrics Society · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Scott J PillaDepartment of Medicine, Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-3292-9047
Jodi B SegalDepartment of Medicine, Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
G Caleb AlexanderDepartment of Medicine, Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Cynthia M BoydDepartment of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Nisa M MaruthurDepartment of Medicine, Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins University · US

Funding

BEHAVIORAL RESEARCH IN HEART &VASCULAR DISEASET32HL007180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MARUTHUR, NISA M · 1985 to 2020
$11.4M
Towards Understanding the Patient Experience of Overuse of Medical ResourcesK24AG049036 · NIA · JOHNS HOPKINS UNIVERSITY · PI SEGAL, JODI B. · 2015 to 2024
$1.6M
Patient-Centered Care for Older Adults with Multiple Chronic Conditions: Research and Mentoring ProgramK24AG056578 · NIA · JOHNS HOPKINS UNIVERSITY · PI BOYD, CYNTHIA MELINDA · 2017 to 2021
$1.1M
NHLBI NIH HHS 5T32HL007180-40NHLBI NIH HHS T32 HL007180NIA NIH HHS 1K24AG049036NIA NIH HHS 1K24AG056578-01NIA NIH HHS K24 AG049036NIA NIH HHS K24 AG056578
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe treatment of type 2 diabetes in older adults requires special considerations including avoidance of hypoglycemia, yet variation in diabetes treatment with aging is not well understood. In this study, we compared nationally representative diabetes treatment patterns and trends between older adults (≥65 y) and younger adults (30-64 y).

designRepeated cross-sectional physician surveys from 2006 to 2015.

settingThe National Ambulatory Medical Care Survey, an annual probability sample of visits to office-based US physicians.

participantsAdults with type 2 diabetes using one or more diabetes medications. MEASUREMENTS: Proportions of visits in which patients treated with each diabetes medication class were compared between older and younger adults in 2-year intervals.

resultsFrom 2006 to 2015, the average number of yearly visits for older and younger adults was 25.4 million and 24.2 million, respectively. In 2014-2015, visits for older compared with younger adults involved less use of metformin (56.0% vs 70.0%; p < .001) and glucagon-like peptide 1 receptor agonists (2.9% vs 6.2%; p = .004), and more use of long-acting insulin (30.2% vs 22.4%; p = .017); other classes were used similarly. During the study period, long-acting insulin use increased markedly in older adults, particularly between 2010 and 2015 where it rose from 12.5% to 30.2% of visits (P-trend <.001). In younger adult visits, long-acting insulin use increased modestly (17.2% to 22.4%) and at a slower rate compared with older adult visits (p < .001).

conclusionThe ambulatory treatment of type 2 diabetes differs between older and younger adults, with the treatment of older adults characterized by low use of newer diabetes medications and a greater and rapidly increasing use of long-acting insulin. These findings call for further research clarifying the comparative effectiveness and safety of newer diabetes medications and long-acting insulin to optimize diabetes care for older patients. J Am Geriatr Soc 67:1066-1073, 2019.

Indexed as

AdultAgedAge DistributionAge FactorsAgingCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHealth Care SurveysHumansHypoglycemic AgentsIncidenceMaleMiddle AgedOffice VisitsHypoglycemic Agentsagedage groupsdiabetes mellitus, type 2/drug therapydiabetes mellitus, type 2/epidemiologydrug utilization

Identifiers

PMID30703251
PMCPMC6488408
OpenAlexW2914451033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.