Evidence map›Paper›PMID 30703119›Full record

ArticlePloS one2019

A qualitative comparison of how older breast cancer survivors process treatment information regarding endocrine therapy.

Huibrie C Pieters, Emily Green, Sally Khakshooy, Miriam Sleven, Annette L Stanton

Abstract readComparative Study
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huibrie C PietersSchool of Nursing, University of California at Los Angeles, Los Angeles, United States of America.ORCID 0000-0003-0929-0668
Emily GreenSchool of Nursing, University of California at Los Angeles, Los Angeles, United States of America.
Sally KhakshooyCedars Sinai Medical Center, Los Angeles, United States of America.
Miriam SlevenTorrance Memorial Medical Center, Torrance, California, United States of America.
Annette L StantonDepartments of Psychology and Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, United States of America.

Funding

Decision making on aromatase inhibitors in breast cancer survivors 65 and olderR21CA167218 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIETERS, HUIBRIE CHRISTELLE · 2013 to 2014
$264k
NCI NIH HHS R21 CA167218
6 · The paper itself

Abstract

backgroundIt remains unclear how information about aromatase inhibitors (AI) impacts women's decision-making about persistence with endocrine therapy. PURPOSE: To describe and compare how women treated for primary early stage breast cancer either persisting or not persisting with an AI received, interpreted, and acted upon AI-related information.

designThematic analysis was used to sort and compare the data into the most salient themes.

participantsWomen (N = 54; 27 persisting, 27 not persisting with an AI) aged 65-93 years took part in qualitative interviews.

resultsWomen in both subgroups described information similarly in terms of its value, volume, type, and source. Aspects of AI-related information that either differed between the subgroups or were misunderstood by one or both subgroups included: (1) knowledge of AI or tamoxifen prior to cancer diagnosis, (2) use of online resources, (3) misconceptions about estrogen, hormone replacement therapies and AI-related symptoms, and (4) risk perception and the meaning and use of recurrence statistics such as Oncotype DX.

conclusionsPersisters and nonpersisters were similar in their desire for more information about potential side effects and symptom management at AI prescription and subsequent appointments. Differences included how information was obtained and interpreted. Interactive discussion questions are shared that can incorporate these findings into clinical settings.

Indexed as

AgedAged, 80 and overAntineoplastic Agents, HormonalAromatase InhibitorsBreast NeoplasmsCancer SurvivorsChemotherapy, AdjuvantDecision MakingFemaleHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMedication AdherencePatient Education as TopicPatient ParticipationTamoxifenAntineoplastic Agents, HormonalAromatase InhibitorsTamoxifen

Identifiers

PMID30703119
PMCPMC6354984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.