Evidence map›Paper›PMID 30703092›Full record

ArticlePLoS neglected tropical diseases2019

A therapeutic preconceptional vaccine against Chagas disease: A novel indication that could reduce congenital transmission and accelerate vaccine development.

Eric Dumonteil, Claudia Herrera, Pierre Buekens

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Vaccines against chronicExpert review of vaccines · 2026
    Review
  3. Article
  4. Inorganic Polyphosphate Is in the Surface ofPathogens (Basel, Switzerland) · 2024
    Article
  5. Chagas Disease in Europe.Tropical medicine and infectious disease · 2023
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia.The American journal of tropical medicine and hygiene · 2019
    Article
  15. Frontiers in microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric DumonteilDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, and Vector Borne and Infectious Disease Research Center, Tulane University, New Orleans, Louisiana, United States of America.ORCID 0000-0001-9376-0209
Claudia HerreraDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, and Vector Borne and Infectious Disease Research Center, Tulane University, New Orleans, Louisiana, United States of America.
Pierre BuekensDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, United States of America.

Funding

Short-course Benznidazole Treatment to Reduce Trypanosoma cruzi Parasitic Load in Women of Reproductive Age: A Non-inferiorityRandomized Controlled TrialR01HD095857 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI BUEKENS, PIERRE, CAFFERATA, MARÍA LUISA · 2018 to 2022
$2.6M
NICHD NIH HHS R01 HD095857
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chagas DiseaseHumansInfectious Disease Transmission, VerticalNitroimidazolesProtozoan VaccinesTrypanocidal AgentsTrypanosoma cruziVaccinationbenzonidazoleNitroimidazolesProtozoan VaccinesTrypanocidal Agents

Identifiers

PMID30703092
PMCPMC6354953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.