Evidence map›Paper›PMID 30702812›Full record

ArticlePediatric obesity2019

Rate of change in body mass index at different ages during childhood and adult obesity risk.

Tao Zhang, Paul K Whelton, Bo Xi, Marie Krousel-Wood, Lydia Bazzano, Jiang He, Wei Chen, Shengxu Li

Abstract read
In one paragraph

Article in Pediatric obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  4. Review
  5. Composition of Breast Milk in Women with Obesity.Journal of clinical medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tao ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong Province, China.
Paul K WheltonDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Bo XiDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong Province, China.
Marie Krousel-WoodDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Lydia BazzanoDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Jiang HeDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Wei ChenDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Shengxu LiChildren's Minnesota Research Institute, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-9210-7283

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI JING CHEN · 2016 to 2026
$25.3M
Childhood CV Risk and Adult CVD Outcomes: an International Long-term Follow-upR01HL121230 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI BURNS, TRUDY L, CHEN, WEI · 2015 to 2019
$13.3M
EVOLUTION OF CARDIOVASCULAR RISK WITH NORMAL AGINGR01AG016592 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2000 to 2015
$11.7M
Childhood Growth, Biological Aging and Midlife Cardio-Metabolic OutcomesR03AG060619 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2018 to 2019
$151k
NHLBI NIH HHS R01 HL121230NHLBI NIH HHS R01HL121230NIA NIH HHS R01 AG016592NIA NIH HHS R03 AG060619NIA NIH HHS R03AG060619NIGMS NIH HHS P20 GM109036NIGMS NIH HHS P20GM109036NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

backgroundChildhood body mass index (BMI) predicts adult obesity. How growth trajectories during childhood relate to adult obesity risk is not well defined.

objectiveWe aimed to characterize BMI growth trajectories from childhood to midlife and to examine the associations between BMI growth rates at childhood age points and adult obesity risk.

methodsThe longitudinal study included 2732 participants with repeated BMI measurements from childhood (4-19 y) to adulthood (20-51 y). A random-effects model was used to construct BMI growth curves by race and sex. Model-estimated levels and linear growth rates of BMI were linked to adult obesity in separate multivariable logistic regression models at individual childhood age points.

resultsBMI followed cubic growth curves. Childhood BMI linear slope estimates were higher in adults with obesity than in adults without obesity (P < 0.001). The association between childhood BMI growth rate and adult obesity was significantly higher in puberty and postpuberty (12-19 y) than in early childhood (4-11 y) with a peak at age 14 (odds ratio = 3.1 and 95% confidence interval, 2.7-3.5).

conclusionsRates of change in BMI at different childhood ages are differentially associated with adult obesity. Puberty and postpuberty are crucial periods for the development of obesity in later life.

Indexed as

Body Mass IndexAdolescentAdultAge FactorsChildChild, PreschoolFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedObesityRiskSexual MaturationYoung Adultbody mass indexgrowth curvelife course epidemiologyobesity

Identifiers

PMID30702812
PMCPMC6684349

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.