ArticleLab on a chip2019
On-chip stool liquefaction via acoustofluidics.
Article in Lab on a chip, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- [High stability enhanced ultrasonic microfluidic structure with flexible tip coupled bubbles].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Article
- Liquid Phase Graphene Exfoliation with a Vibration-Based Acoustofluidic Effector.Micromachines · 2023Article
- Manipulation with sound and vibration: A review on the micromanipulation system based on sub-MHz acoustic waves.Ultrasonics sonochemistry · 2023Review
- Manipulation of single cells via a Stereo Acoustic Streaming Tunnel (SteAST).Microsystems & nanoengineering · 2022Article
- Fabrication of tunable, high-molecular-weight polymeric nanoparticlesLab on a chip · 2021Article
- On-site genetic analysis for species identification using lab-on-a-chip.Ecology and evolution · 2021Article
- Contactless acoustic micro/nano manipulation: a paradigm for next generation applications in life sciences.Proceedings. Mathematical, physical, and engineering sciences · 2020Review
- What can microfluidics do for human microbiome research?Biomicrofluidics · 2020Article
- Acoustic Microfluidics.Annual review of analytical chemistry (Palo Alto, Calif.) · 2020Review
- A disposable acoustofluidic chip for nano/microparticle separation using unidirectional acoustic transducers.Lab on a chip · 2020Article
- An acoustofluidic device for efficient mixing over a wide range of flow rates.Lab on a chip · 2020Article
- Article
- Acoustic tweezers based on circular, slanted-finger interdigital transducers for dynamic manipulation of micro-objects.Lab on a chip · 2020Article
- Acoustofluidic Synthesis of Particulate Nanomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- Highly integrated microfluidic device for cell pairing, fusion and culture.Biomicrofluidics · 2019Article
- Acoustofluidic methods in cell analysis.Trends in analytical chemistry : TRAC · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors.
Funding
Abstract
Microfluidic-based portable devices for stool analysis are important for detecting established biomarkers for gastrointestinal disorders and understanding the relationship between gut microbiota imbalances and various health conditions, ranging from digestive disorders to neurodegenerative diseases. However, the challenge of processing stool samples in microfluidic devices hinders the development of a standalone platform. Here, we present the first microfluidic chip that can liquefy stool samples via acoustic streaming. With an acoustic transducer actively generating strong micro-vortex streaming, stool samples and buffers in microchannel can be homogenized at a flow rate up to 30 μL min-1. After homogenization, an array of 100 μm wide micropillars can further purify stool samples by filtering out large debris. A favorable biocompatibility was also demonstrated for our acoustofluidic-based stool liquefaction chip by examining bacteria morphology and viability. Moreover, stool samples with different consistencies were liquefied. Our acoustofluidic chip offers a miniaturized, robust, and biocompatible solution for stool sample preparation in a microfluidic environment and can be potentially integrated with stool analysis units for designing portable stool diagnostics platforms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.