Evidence map›Paper›PMID 30702707›Full record

ArticleOptics letters2019

Handheld line-scanned dual-axis confocal microscope with pistoned MEMS actuation for flat-field fluorescence imaging.

Linpeng Wei, Chengbo Yin, Yoko Fujita, Nader Sanai, Jonathan T C Liu

Abstract read
In one paragraph

Article in Optics letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linpeng Wei
Chengbo Yin
Yoko Fujita
Nader Sanai
Jonathan T C Liu

Funding

Line-scanned MEMS-based dual-axis confocal microscopy to detect oral lesions in vR01DE023497 · NIDCR · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C. · 2012 to 2014
$2.4M
Intraoperative confocal microscopy for quantitative delineation of low-grade glioR01CA175391 · NCI · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C., SANAI, NADER · 2014 to 2018
$1.7M
NCI NIH HHS R01 CA175391NIDCR NIH HHS R01 DE023497
6 · The paper itself

Abstract

A handheld line-scanned dual-axis confocal (LS-DAC) microscope has been developed for high-speed (16 frames/s) fluorescence imaging of tissues with sub-nuclear resolution. This is the first miniature fluorescence LS-DAC system that has been fully packaged for handheld clinical use on patients. A novel micro-electro-mechanical system scanning mechanism, with synchronized tilting and pistoning, is used to achieve flat-field en face imaging. We show that this facilitates video mosaicking to generate images that sample an extended lateral field of view.

Indexed as

Micro-Electrical-Mechanical SystemsAnimalsEquipment DesignImage Processing, Computer-AssistedKidneyMiceMicroscopy, ConfocalOptical Imaging

Identifiers

PMID30702707
PMCPMC7723749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.