ArticleeLife2019
Quantitative uniqueness of human brain evolution revealed through phylogenetic comparative analysis.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Organizers in a dish: Modeling human CNS morphogenesis.Developmental cell · 2026Review
- Genetic Insights into Head-to-Body Ratios Via Deep Learning-Based Image Segmentation and Implications for Common Diseases.Nature communications · 2025Article
- Macroevolutionary brain scaling is a microevolutionary metaphenomenon.Nature communications · 2025Article
- Hominin brain size increase has emerged from within-species encephalization.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The reduction in relative brain size in the domesticated dog is not an evolutionary singularity among the canids.Biology letters · 2024Article
- Co-evolutionary dynamics of mammalian brain and body size.Nature ecology & evolution · 2024Article
- Insights into the genetic architecture of cerebellar lobules derived from the UK Biobank.Scientific reports · 2024Article
- Article
- A Comparative Perspective on the Cerebello-Cerebral System and Its Link to Cognition.Cerebellum (London, England) · 2023Review
- Both Diet and Sociality Affect Primate Brain-Size Evolution.Systematic biology · 2023Article
- From fossils to mind.Communications biology · 2023Review
- Neuroplasticity enables bio-cultural feedback in Paleolithic stone-tool making.Scientific reports · 2023Article
- Scaling Principles of White Matter Connectivity in the Human and Nonhuman Primate Brain.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Mammalian tumor-like organs. 1. The role of tumor-like normal organs and atypical tumor organs in the evolution of development (carcino-evo-devo).Infectious agents and cancer · 2022Review
- Diffusion MRI data, sulcal anatomy, and tractography for eight species from the Primate Brain Bank.Brain structure & function · 2021Article
- A Connectomic Hypothesis for the Hominization of the Brain.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- The Evolutionary History of Common Genetic Variants Influencing Human Cortical Surface Area.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Runaway brain-culture coevolution as a reason for larger brains: Exploring the "cultural drive" hypothesis by computer modeling.Ecology and evolution · 2020Article
- Human Social Evolution: Self-Domestication or Self-Control?Frontiers in psychology · 2020Article
- Cerebral cortical folding, parcellation, and connectivity in humans, nonhuman primates, and mice.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
While the human brain is clearly large relative to body size, less is known about the timing of brain and brain component expansion within primates and the relative magnitude of volumetric increases. Using Bayesian phylogenetic comparative methods and data for both extant and fossil species, we identified that a distinct shift in brain-body scaling occurred as hominins diverged from other primates, and again as humans and Neanderthals diverged from other hominins. Within hominins, we detected a pattern of directional and accelerating evolution towards larger brains, consistent with a positive feedback process in the evolution of the human brain. Contrary to widespread assumptions, we found that the human neocortex is not exceptionally large relative to other brain structures. Instead, our analyses revealed a single increase in relative neocortex volume at the origin of haplorrhines, and an increase in relative cerebellar volume in apes.
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Registered trials
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