ArticleInternational review of psychiatry (Abingdon, England)2019
Examining the relationship between perinatal depression and neurodevelopment in infants and children through structural and functional neuroimaging research.
Article in International review of psychiatry (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Effectiveness of digital psychological interventions in reducing perinatal depression: a systematic review of meta-analyses.Archives of women's mental health · 2023Pooled it
- Parenting as a Mediator of Associations between Depression in Mothers and Children's Functioning: A Systematic Review and Meta-Analysis.Clinical child and family psychology review · 2020Pooled it
- The Eph-ephrin system in neuropsychiatric and neurodevelopmental disorders.Journal of psychiatry & neuroscience : JPN · 2026Review
- The promise of infant MRI in psychiatry: toward a framework for neural network measures in early emotional and behavioral risk identification and new intervention targets.Molecular psychiatry · 2026Review
- Plasma orexin-A levels in women with postpartum depression: a prospective controlled study.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Maternal symptoms of prenatal depression predict context-incongruent negative emotion in infants.Emotion (Washington, D.C.) · 2024Article
- Antenatal anxiety symptoms outperform antenatal depression symptoms and suicidal ideation as a risk factor for postpartum suicidal ideation.Anxiety, stress, and coping · 2024Article
- Exploring the Relationship between Neuroticism and Perinatal Depressive Symptoms: Findings from a 2-Year, Multicenter Study in Italy.Brain sciences · 2024Article
- Genetic and Epigenetic Factors Associated with Postpartum Psychosis: A 5-Year Systematic Review.Journal of clinical medicine · 2024Review
- Early intervention to prevent adverse child emotional and behavioural development following maternal depression in pregnancy: study protocol for a randomised controlled trial.BMC psychology · 2023Article
- Prenatal and early-life environmental factors, family demographics and cortical brain anatomy in 5-year-olds: an MRI study from FinnBrain Birth Cohort.Brain imaging and behavior · 2022Article
- Perinatal exposure to fluoxetine and maternal adversity affect myelin-related gene expression and epigenetic regulation in the corticolimbic circuit of juvenile rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Recent Neuroscience Advances in Human Parenting.Advances in neurobiology · 2022Article
- Low and mismatched socioeconomic status between newlyweds increased their risk of depressive symptoms: A multi-center study.Frontiers in psychiatry · 2022Article
- Adverse childhood experiences predict neurite density differences in young children with and without attention deficit hyperactivity disorder.Developmental psychobiology · 2022Article
- Exploring the relationship between maternal prenatal stress and brain structure in premature neonates.PloS one · 2021Article
- Neurobiology of peripartum mental illness.Handbook of clinical neurology · 2021Review
- Adaptations in reward-related behaviors and mesolimbic dopamine function during motherhood and the postpartum period.Frontiers in neuroendocrinology · 2020Review
- The Long-Term Impact of Maternal Anxiety and Depression Postpartum and in Early Childhood on Child and Paternal Mental Health at 11-12 Years Follow-Up.Frontiers in psychiatry · 2020Article
- Experiences of Discrimination and Depression Trajectories over Pregnancy.Women's health issues : official publication of the Jacobs Institute of Women's HealthArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Depression is the most common perinatal psychiatric disorder, but little is known about how it may impact offspring neurodevelopment, as well as the mechanisms by which it may confer transgenerational psychiatric risk. This review presents imaging studies conducted to evaluate the relationship between perinatal depression (PND) and infant and child neurodevelopment. Altered structural and functional connectivity is implicated in children exposed to PND and anxiety. Overall, there are changes in connectivity between amygdala and the prefrontal cortex. Studies suggest decreased hippocampal growth in the first 6 months after birth, decreased cortical thickness in children, and increased amygdala volumes, that are more pronounced in female offspring. Future research is needed to understand the impact of PND on development so that early interventions which promote mother-infant bonding and cognitive development may improve developmental outcomes in children exposed to PND, reducing later risk of psychopathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.