Evidence map›Paper›PMID 30701569›Full record

ArticleBritish journal of clinical pharmacology2020

Pharmacokinetic herb-drug interaction between ginger and crizotinib.

Bruno Revol, Elodie Gautier-Veyret, Capucine Arrivé, Nathalie Fouilhé Sam-Laï, Anne McLeer-Florin, Hélène Pluchart, Julian Pinsolle, Anne-Claire Toffart

Abstract readLetter
In one paragraph

Article in British journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Modulation of Hepatic Functions by Chicory (Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Polyphenol-Rich Ginger (Molecules (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Pharmacokinetic herb-drug interaction between ginger and crizotinib.British journal of clinical pharmacology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Bruno RevolCentre Régional de Pharmacovigilance, Pôle Santé Publique, CHU Grenoble Alpes, France.ORCID 0000-0003-2931-2940
Elodie Gautier-VeyretHP2, INSERM U1042, Université Grenoble Alpes, France.
Capucine ArrivéPôle Pharmacie, CHU Grenoble Alpes, France.
Nathalie Fouilhé Sam-LaïCentre Régional de Pharmacovigilance, Pôle Santé Publique, CHU Grenoble Alpes, France.
Anne McLeer-FlorinPôle de Biologie et Pathologie, CHU Grenoble Alpes, France.
Hélène PluchartPôle Pharmacie, CHU Grenoble Alpes, France.
Julian PinsolleUniversité Grenoble Alpes, France.
Anne-Claire ToffartInstitute for Advanced Biosciences, UGA/INSERM U1209/CNRS 5309, Université Grenoble Alpes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of complementary and alternative medicine at least once during or after cancer treatment has increased over the past years from an estimated 25% in the 1970s and 1980s to more than 32% in the 1990s and to 49% after 2000. The risk of herb-drug interaction is therefore increasingly recognized as a public health problem. To the best of our knowledge, we report here the first case of interaction between ginger and anticancer drug, with serious consequences for the patient. There is an urgent need regarding complementary and alternative medicine: Both clinicians and patients should be aware of the potential interactions between herbs and prescribed drugs.

Indexed as

Antineoplastic AgentsCrizotinibHerb-Drug InteractionsZingiber officinaleHumansAntineoplastic AgentsCrizotinib

Identifiers

PMID30701569
PMCPMC7444772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.