ReviewCurrent environmental health reports2019
Biomonitoring and Nonpersistent Chemicals-Understanding and Addressing Variability and Exposure Misclassification.
Review in Current environmental health reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Temporal exposure and consistency of endocrine disrupting chemicals in a longitudinal study of individuals with impaired fasting glucose.Environmental research · 2021Pooled it
- Endocrine-Disrupting Chemicals and Hypertension: Mechanisms and Clinical Implications.Journal of cardiovascular development and disease · 2026Review
- Biomonitoring-based exposure assessment of phthalate and non-phthalate plasticizers: methodological insights from a 7-day consecutive sampling case study in Korea.Journal of exposure science & environmental epidemiology · 2026Article
- Improving the design of epidemiology studies that use biomonitoring for exposure assessment: a SciPinion panel recommendation.BMC medical research methodology · 2026Article
- Year-to-year variation in phthalate metabolites in the Midlife Women's Health Study.Journal of exposure science & environmental epidemiology · 2024Article
- Exposure assessment of dairy cows to parabens using hair samples analysis.Scientific reports · 2024Article
- Advancing Global Health Surveillance of Mycotoxin Exposures using Minimally Invasive Sampling Techniques: A State-of-the-Science Review.Environmental science & technology · 2024Review
- The Role of Endocrine Disruptors Bisphenols and Phthalates in Obesity: Current Evidence, Perspectives and Controversies.International journal of molecular sciences · 2024Review
- Prenatal exposures to endocrine disrupting chemicals: The role of multi-omics in understanding toxicity.Molecular and cellular endocrinology · 2023Review
- Urinary phenol concentrations and fecundability and early pregnancy loss.Human reproduction (Oxford, England) · 2023Article
- Interpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working group's health-based guidance value (HB2GV) dashboard.International journal of hygiene and environmental health · 2023Article
- Article
- Silicone Wristbands in Exposure Assessment: Analytical Considerations and Comparison with Other Approaches.International journal of environmental research and public health · 2022Review
- Quo vadis blood protein adductomics?Archives of toxicology · 2022Review
- Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples.Environmental pollution (Barking, Essex : 1987) · 2021Article
- Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study.Environmental geochemistry and health · 2021Article
- Pyrethroid exposure among children residing in green versus non-green multi-family, low-income housing.Journal of exposure science & environmental epidemiology · 2021Article
- Impact of Endocrine-Disrupting Chemicals in Breast Milk on Postpartum Depression in Korean Mothers.International journal of environmental research and public health · 2021Article
- Comparison of strategies to efficiently combine repeated urine samples in biomarker-based studies.Environmental research · 2021Article
- How Many Urine Samples Are Needed to Accurately Assess Exposure to Non-Persistent Chemicals? The Biomarker Reliability Assessment Tool (BRAT) for Scientists, Research Sponsors, and Risk Managers.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewWe offer here a review of intraindividual variability in urinary biomarkers for assessing exposure to nonpersistent chemicals. We provide thoughts on how to better evaluate exposure to nonpersistent chemicals. RECENT
findingsWe summarized reported values of intraclass correlation coefficients and found that most values fall into categories that indicate only poor to good reproducibility. Even within the "good" classification, a large percentage of study participants is likely to be misclassified as to their exposure. There is sufficient information to support the statement that studies using only one spot measurement of a nonpersistent chemical will be unreliable. It is unequivocal that multiple samples have to be collected over a period of toxicological relevance and with consideration of exposure patterns. Sponsors of research and researchers themselves should be vocal about ensuring that sufficient resources are made available to properly characterize exposures when studying nonpersistent chemicals. Otherwise, we will continue to see an ever-growing body of literature yielding inconsistent and/or uninterpretable results.
Indexed as
Identifiers
30701410What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.