Evidence map›Paper›PMID 30701310›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2019

Reoperation following lumbar spinal surgery: costs and outcomes in a UK population cohort study using the Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES).

Sharada Weir, Tzu-Chun Kuo, Mihail Samnaliev, Travis S Tierney, Andrea Manca, Rod S Taylor, Julie Bruce, Sam Eldabe, David Cumming

Open access · greenAbstract read
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Sharada WeirPHMR, Ltd., Bldg D, Berkeley Works, Berkley Grove, London, NW1 8XY, UK. sharadaweir@phmr.com.ORCID 0000-0002-3206-6034
Tzu-Chun KuoPHMR, Ltd., Bldg D, Berkeley Works, Berkley Grove, London, NW1 8XY, UK.
Mihail SamnalievHarvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
Travis S TierneyCentre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College, Du Cane Road, London, W120NN, UK.
Andrea MancaCentre for Health Economics, Alcuin A, University of York, York, YO10 5DD, UK.
Rod S TaylorInstitute of Health Research, University of Exeter Medical School, South Cloisters, St Lukes Campus, Heavitree Road, Exeter, EX1 2LU, UK.
Julie BruceWarwick Clinical Trials Unit, Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.
Sam EldabeDepartment of Pain Medicine, Cheriton House, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3 BW, UK.
David CummingTrauma and Orthopaedics Department, Ipswich Hospital, Heath Road, Ipswich, Suffolk, IP4 5PD, UK.
Boston Children's Hospital · USCJR Propulsion (United Kingdom) · GBIpswich Hospital · GBJames Cook University Hospital · GBNational Milk Records (United Kingdom) · GBUniversity of Exeter · GBUniversity of Warwick · GBUniversity of York · GB

Funding

Medical Research Council G106/1178
6 · The paper itself

Abstract

purposeTo assess the likelihood of persistent postoperative pain (PPP) following reoperation after lumbar surgery and to estimate associated healthcare costs.

methodsThis is a retrospective cohort study using two linked UK databases: Hospital Episode Statistics and UK Clinical Practice Research Datalink. Costs and outcomes associated with reoperation were evaluated over a 2-year postoperative period using multivariate logistic regression for cases who underwent reoperation and controls who did not, based on demographics, index surgery type, smoking status, and pre-index comorbidities using propensity score matching.

resultsRisk factors associated with reoperation included younger age and the presence of diabetes with complications or rheumatic disease. The rate of PPP after reoperation was much higher than after index surgery, with 79 of 200 (39.5%; 95% CI 32.5%, 46.5%) participants experiencing ongoing pain compared with 983 of 5022 (19.5%; 95% CI 18.5%, 20.7%) after index surgery. Mean costs in the 2 years following reoperation were £1889 higher (95% CI £2, £3809) than for patients with PPP who did not undergo repeat surgery over an equivalent follow-up period. With the cost of reoperation itself included, the mean cost difference for patients who underwent reoperation compared with matched controls rose to £7221 (95% CI £5273, £9206).

conclusionsHigh rates of PPP and associated healthcare costs suggest that returning to the operating room is a complex and challenging decision. Spinal surgeons should review whether the potential benefits of additional surgery are justified when other approaches to managing and relieving chronic pain have demonstrated superior outcomes. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

AdultAgedCohort StudiesFemaleHealth Care CostsHumansLogistic ModelsLumbar VertebraeMaleMiddle AgedNeurosurgical ProceduresOrthopedic ProceduresPostoperative PainPropensity ScoreReoperationRetrospective StudiesCostLumbar surgeryPersistent postoperative painReoperation

Identifiers

PMID30701310
OpenAlexW2913562926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.