Evidence map›Paper›PMID 30701304›Full record

ArticleEuropean journal of nutrition2020

Microbial insight into dietary protein source affects intestinal function of pigs with intrauterine growth retardation.

Lianqiang Che, Liang Hu, Qiang Zhou, Xie Peng, Yang Liu, Yuheng Luo, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Dietary supplementation withFrontiers in veterinary science · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Lianqiang CheInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China. clianqiang@hotmail.com.ORCID http://orcid.org/0000-0001-5263-9314
Liang HuInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Qiang ZhouInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Xie PengInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Yang LiuInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Yuheng LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Zhengfeng FangInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Yan LinInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Shengyu XuInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Bin FengInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Jian LiInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Jiayong TangInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
De WuInstitute of Animal Nutrition, Sichuan Agricultural University, Ya'an, Sichuan, China.
Ministry of Education of the People's Republic of China · CN

Funding

International Cooperation in Science and Technology Project of Sichuan Province 2014HH0034National Natural Science Foundation of China 31101727Natural Science Foundation of sichuan Province (CN) 12ZA110
6 · The paper itself

Abstract

purposeDietary protein, as important macronutrient, is vital for intestinal function and health status. We aimed to determine the effects of dietary protein source on growth performance and intestinal function of neonates with intrauterine growth retardation (IUGR) in a pig model.

methodsEighteen pairs of IUGR and normal birth weight (NBW) weaned pigs were allotted to be fed starter diet containing soybean protein concentrate (SPC) or spray-dried porcine plasma (SDPP) for 2 weeks. Growth performance, antioxidant variables, intestinal morphology and absorption capability, microbiota composition and short-chain fatty acids (SCFA) were assessed.

resultsIUGR led to poor growth performance, absorption capability and changes on antioxidant variables, while SDPP diet improved the growth performance, diarrhea index, intestinal morphology and antioxidant variables of IUGR or NBW pigs relative to that fed SPC diet. Importantly, SDPP diet improved bacterial diversity and increased the abundance of phylum Firmicutes, but decreased the phylum Proteobacteria in colonic digesta, associating with higher genera Lactobacillus and lower genera Escherichia-Shigella, linking to the increased concentration of SCFA.

conclusionsOur findings indicate that IUGR impairs the growth rate, intestinal function and oxidative status of weaned pigs, which could be partly improved by SDPP diet either for IUGR or NBW pigs, associating with the better antioxidant capability, composition of microbiotas and their metabolites.

Indexed as

Animal Nutritional Physiological PhenomenaAnimal FeedAnimalsAnimals, NewbornDietary ProteinsDisease Models, AnimalFetal Growth RetardationIntestinesSwineDietary ProteinsBacteriaLow birth weightOxidative stressPigProtein source

Identifiers

PMID30701304
OpenAlexW2914103778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.