Evidence map›Paper›PMID 30701201›Full record

ArticleCommunications biology2019

Action and mechanism of the colistin resistance enzyme MCR-4.

Huimin Zhang, Mengyun Hou, Yongchang Xu, Swaminath Srinivas, Man Huang, Lizhang Liu, Youjun Feng

Abstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Virulence · 2026
    Review
  2. A functionally selectedApplied and environmental microbiology · 2026
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  3. Article
  4. Article
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  6. Review
  7. Review
  8. A functionally selectedbioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Orthopedic infections associated with distinctFrontiers in cellular and infection microbiology · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huimin Zhang *1Department of Pathogen Biology & Microbiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 China.
Mengyun Hou *1Department of Pathogen Biology & Microbiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 China.
Yongchang Xu *1Department of Pathogen Biology & Microbiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 China.
Swaminath Srinivas *3Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801 USA.
Man Huang2Department of General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 China.
Lizhang Liu1Department of Pathogen Biology & Microbiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 China.
Youjun Feng1Department of Pathogen Biology & Microbiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin is the last-resort antibiotic against lethal infections with multidrug-resistant bacterial pathogens. A rainbow coalition of mobile colistin resistance (

Indexed as

Amino Acid SequenceColistinEvolution, MolecularGain of Function MutationModels, MolecularPhylogenyProtein ConformationProteolysisStructure-Activity RelationshipTransferases (Other Substituted Phosphate Groups)ColistinTransferases (Other Substituted Phosphate Groups)

Identifiers

PMID30701201
PMCPMC6347640

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.