Evidence map›Paper›PMID 30701133›Full record

ArticlePeerJ2019

Isolation of wheat bran-colonizing and metabolizing species from the human fecal microbiota.

Kim De Paepe, Joran Verspreet, Mohammad Naser Rezaei, Silvia Hidalgo Martinez, Filip Meysman, Davy Van de Walle, Koen Dewettinck, Jeroen Raes, Christophe Courtin, Tom Van de Wiele

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Nutrients · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Kim De PaepeFaculty of Bioscience Engineering, Department of Biotechnology, Center for Microbial Ecology and Technology (CMET), Universiteit Gent, Gent, Belgium.
Joran VerspreetFaculty of Bioscience Engineering, Leuven Food Science and Nutrition Research Centre (LFoRCe), Laboratory of Food Chemistry and Biochemistry, KU Leuven, Heverlee, Belgium.
Mohammad Naser RezaeiFaculty of Bioscience Engineering, Leuven Food Science and Nutrition Research Centre (LFoRCe), Laboratory of Food Chemistry and Biochemistry, KU Leuven, Heverlee, Belgium.
Silvia Hidalgo MartinezFaculty of Sciences, Department of Biology, Ecosystem Management Research Group (ECOBE), Universiteit Antwerpen, Antwerpen, Belgium.
Filip MeysmanFaculty of Sciences, Department of Biology, Ecosystem Management Research Group (ECOBE), Universiteit Antwerpen, Antwerpen, Belgium.
Davy Van de WalleFaculty of Bioscience Engineering, Department of Food Technology, Safety and Health, Laboratory of Food Technology and Engineering (FTE), Universiteit Gent, Gent, Belgium.
Koen DewettinckFaculty of Bioscience Engineering, Department of Food Technology, Safety and Health, Laboratory of Food Technology and Engineering (FTE), Universiteit Gent, Gent, Belgium.
Jeroen RaesDepartment of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Christophe CourtinFaculty of Bioscience Engineering, Leuven Food Science and Nutrition Research Centre (LFoRCe), Laboratory of Food Chemistry and Biochemistry, KU Leuven, Heverlee, Belgium.
Tom Van de WieleFaculty of Bioscience Engineering, Department of Biotechnology, Center for Microbial Ecology and Technology (CMET), Universiteit Gent, Gent, Belgium.
Ghent University · BEKU Leuven · BEDelft University of Technology · NLFlemish Institute for Technological Research · BERega Institute for Medical Research · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undigestible, insoluble food particles, such as wheat bran, are important dietary constituents that serve as a fermentation substrate for the human gut microbiota. The first step in wheat bran fermentation involves the poorly studied solubilization of fibers from the complex insoluble wheat bran structure. Attachment of bacteria has been suggested to promote the efficient hydrolysis of insoluble substrates, but the mechanisms and drivers of this microbial attachment and colonization, as well as subsequent fermentation remain to be elucidated. We have previously shown that an individually dependent subset of gut bacteria is able to colonize the wheat bran residue. Here, we isolated these bran-attached microorganisms, which can then be used to gain mechanistic insights in future pure culture experiments. Four healthy fecal donors were screened to account for inter-individual differences in gut microbiota composition. A combination of a direct plating and enrichment method resulted in the isolation of a phylogenetically diverse set of species, belonging to the

Indexed as

EnrichmentHuman gut microbiotaInsoluble dietary particlesWheat bran-attached microbiotaWheat bran-utilizing microbiota

Identifiers

PMID30701133
PMCPMC6348960
OpenAlexW2912551764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.