Evidence map›Paper›PMID 30701013›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2017

Imaging of Biomolecular NMR Signals Amplified by Reversible Exchange with Parahydrogen Inside an MRI Scanner.

Kirill V Kovtunov, Bryce E Kidd, Oleg G Salnikov, Liana B Bales, Max E Gemeinhardt, Jonathan Gesiorski, Roman V Shchepin, Eduard Y Chekmenev, Boyd M Goodson, Igor V Koptyug

Abstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Synthesis andChemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
  5. Article
  6. Multiple Quantum Coherences Hyperpolarized at Ultra-Low Fields.Chemphyschem : a European journal of chemical physics and physical chemistry · 2019
    Article
  7. Chemistry (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  8. Chemistry (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  9. Review
  10. Quasi-Resonance Signal Amplification by Reversible Exchange.The journal of physical chemistry letters · 2018
    Article
  11. The journal of physical chemistry. C, Nanomaterials and interfaces · 2018
    Article
  12. Article
  13. Review
  14. Article
  15. SpontaneousThe journal of physical chemistry letters · 2018
    Article
  16. Spin Relays Enable Efficient Long-Range Heteronuclear Signal Amplification By Reversible Exchange.The journal of physical chemistry. C, Nanomaterials and interfaces · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kirill V KovtunovInternational Tomography Center SB RAS, Novosibirsk, 630090, Russia.
Bryce E KiddDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901, USA.
Oleg G SalnikovInternational Tomography Center SB RAS, Novosibirsk, 630090, Russia.
Liana B BalesDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901, USA.
Max E GemeinhardtDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901, USA.
Jonathan GesiorskiDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901, USA.
Roman V ShchepinVanderbilt Institute of Imaging Science (VUIIS), Department of Radiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Eduard Y ChekmenevDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901, USA.
Boyd M GoodsonDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901, USA.
Igor V KoptyugInternational Tomography Center SB RAS, Novosibirsk, 630090, Russia.

Funding

Pure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB020323 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2015 to 2016
$416k
Pure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB018014 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2014 to 2015
$407k
Magnetic Resonance Spectroscopy and Molecular Imaging of Metabolic Pathways in CancerR21CA220137 · NCI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2017 to 2019
$390k
NCI NIH HHS R21 CA220137NIBIB NIH HHS R21 EB018014NIBIB NIH HHS R21 EB020323
6 · The paper itself

Abstract

The Signal Amplification by Reversible Exchange (SABRE) technique employs exchange with singlet-state parahydrogen to efficiently generate high levels of nuclear spin polarization. Spontaneous SABRE has been shown previously to be efficient in the milli-Tesla and micro-Tesla regimes. We have recently demonstrated that high-field SABRE is also possible, where proton sites of molecules that are able to reversibly coordinate to a metal center can be hyperpolarized directly within high-field magnets, potentially offering the convenience of

Identifiers

PMID30701013
PMCPMC6349396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.