Observational studyWorld journal of gastroenterology2019
Adenoma and advanced neoplasia detection rates increase from 45 years of age.
Observational study in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Quality indicators for colonoscopy.Gastrointestinal endoscopy · 2024Guideline
- Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Guideline
- Efficacy and safety of ciprofol versus remimazolam combined with alfentanil for sedation during outpatient colonoscopy: a randomized double-blind noninferiority trial.Brazilian journal of anesthesiology (Elsevier) · 2026Article
- Colorectal Cancer Screening at 40: Real Benefit or Justifiable Cost?GE Portuguese journal of gastroenterology · 2026Article
- Adenoma detection rates and complications of colonoscopy in patients aged 75 to 79 vs 70 to 74 years: Propensity score-matching study.Endoscopy international open · 2026Article
- Insights from age-stratified endoscopic detection metrics support initiating colorectal cancer screening at age 45.BMC gastroenterology · 2025Article
- Traditional and Novel Colonoscopy Quality Metrics: What's Important in 2025.Current gastroenterology reports · 2025Review
- Establishment and validation of a clinical prediction model for colorectal adenoma risk factors.Oncology letters · 2025Article
- When Should Colon Cancer Screening Begin? The Impact of Early-Onset Colorectal Cancer and the Reality of an Unscreened Older Population.Digestive diseases and sciences · 2025Review
- Colorectal Neoplasia in Vietnamese Patients Under 50 Years of Age: A Cross-Sectional Study.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Article
- Quality Indicators for Colonoscopy.The American journal of gastroenterology · 2024Article
- Characteristics of adenomatous colorectal polyps among a Saudi population.Journal of Taibah University Medical Sciences · 2023Article
- Key quality indicators in colonoscopy.Gastroenterology report · 2023Review
- Publication trends and hotspots of colorectal adenoma during 2002-2022: a bibliometric and visualized analysis.Frontiers in oncology · 2023Article
- A progressive three-state model to estimate time to cancer: a likelihood-based approach.BMC medical research methodology · 2022Article
- Narrow band imaging versus white light for detecting sessile serrated lesion: A prospective randomized multicenter study.DEN open · 2022Article
- Texture and color enhancement imaging in magnifying endoscopic evaluation of colorectal adenomas.World journal of gastrointestinal endoscopy · 2022Article
- Colorectal Cancer Screening with Computed Tomography Colonography: Single Region Experience in Kazakhstan.Clinical endoscopy · 2022Article
- Retrospective study of risk factors for colorectal adenomas and non-adenomatous polyps.Translational cancer research · 2020Article
- Molecular Aspects of Colorectal Adenomas: The Interplay among Microenvironment, Oxidative Stress, and Predisposition.BioMed research international · 2020Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColonoscopy is considered a valid primary screening tool for colorectal cancer (CRC). The decreasing risk of CRC observed in patients undergoing colonoscopy is correlated with the adenoma detection rate (ADR). Due to the fact that screening programs usually start from the age of 50, very few data are available on the risk of adenoma between 40 and 49 years. However, the incidence of CRC is increasing in young populations and it is not uncommon in routine practice to detect adenomas or even advanced neoplasia during colonoscopy in patients under 50 years.
aimTo compare the ADR and advanced neoplasia detection rate (ANDR) according to age in a large series of patients during routine colonoscopy.
methodsAll consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were as follows: patients scheduled for partial colonoscopy or interventional colonoscopy (for stent insertion or stenosis dilation). Colonoscopies were performed in our unit by a team of 30 gastroenterologists in 2016. We determined the ADR and ANDR in each age group in the whole population and in the population with an average risk of CRC (excluding patients with personal or family history of advanced adenoma or cancer).
results6027 colonoscopies were performed in patients with a median age of 57 years (range, 15-96). The ADR and ANDR were 28.6% and 9.7%, respectively, in the whole population. When comparing patients aged 40-44 (
conclusionThis study shows a significant two-fold increase in the ADR and ANDR in patients aged 45 years and over.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.