ReviewWorld journal of gastroenterology2019
Esophagogastric junction outflow obstruction: Where are we now in diagnosis and management?
Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06588348 (Corticosteroid Effect on Achalasia Variant Esophagogastric Junction Outflow Obstruction), which is not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Corticosteroid Effect on Achalasia Variant Esophagogastric Junction Outflow Obstruction
Who cites it
28 citing papers in PubMed.
- Timed Barium Esophagography in Esophagogastric Junction Outflow Obstruction: A Retrospective Radiologic Assessment.Diagnostics (Basel, Switzerland) · 2026Article
- Review
- Effect of carbonated water on esophageal high-resolution manometry metrics: a retrospective study.BMC gastroenterology · 2025Article
- Article
- Functional Lumen Imaging Probe Measurement Post-Pneumatic Dilation in Clinically Relevant Esophagogastric Junction Outlet Obstruction.Neurogastroenterology and motility · 2025Article
- Esophageal motility disorders other than achalasia.Abdominal radiology (New York) · 2025Review
- Clinical characteristics and esophageal motility in patients with gastric cardia submucosal tumors and associated changes after endoscopic resection.Surgical endoscopy · 2025Article
- Serosal overturning assisted endoscopic full-thickness mucosal resection of extraneous giant mass at the esophagogastric junction.Clinical case reports · 2024Article
- Efficacy of peroral endoscopic myotomy for the treatment of functional esophagogastric junction outflow obstruction.iGIE : innovation, investigation and insights · 2023Article
- Mixed Esophageal Disease (MED): A New Concept.Digestive diseases and sciences · 2023Review
- Esophageal Dysfunction in Post-lung Transplant: An Enigma.Dysphagia · 2023Review
- Per-oral endoscopic myotomy for the treatment of non-achalasia esophageal dysmotility disorders: experience from a single high-volume center.Surgical endoscopy · 2023Article
- Changes in the esophagogastric junction outflow obstruction manometric feature based on the Chicago Classification updates.World journal of gastroenterology · 2022Article
- Can FLIP guide therapy in idiopathic esophagogastric junction outflow obstruction?Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022Article
- The treatment effects of acotiamide in esophagogastric outflow obstruction: a prospective longitudinal observational study.Esophagus : official journal of the Japan Esophageal Society · 2022Observational
- Esophageal-Gastric Junction Outflow Obstruction: Are Clinicians Treating New Diseases or Treating New Findings from Old Diseases?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Upright Integrated Relaxation Pressure Predicts Symptom Outcome for Esophagogastric Junction Outflow Obstruction.Journal of neurogastroenterology and motility · 2021Article
- Provider Variability in the Management Patterns of Increased Nonacid Reflux.Digestive diseases and sciences · 2021Article
- Assessing the Frequency and Risk Factors Associated with Gastroesophageal Reflux Disease (GERD) in Southern Punjab, Pakistan.Risk management and healthcare policy · 2021Article
- Ultrasonography in the diagnosis and monitoring of intra-abdominal hypertension and abdominal compartment syndrome: Ultrasonografia a nadciśnienie wewnątrzbrzuszne i zespół przedziału brzusznego.Journal of ultrasonography · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophagogastric junction outflow obstruction (EGJOO) is a major motility disorder based on the Chicago Classification of esophageal motility disorders. This entity involves a heterogenous group of underlying etiologies. The diagnosis is reached by performing high-resolution manometry. This reveals evidence of obstruction at the esophagogastric junction, manifested by an elevated integrated relaxation pressure (IRP) above a cutoff value (IRP threshold varies by the manometric technology and catheter used), with preserved peristalsis. Further tests like endoscopy, timed barium esophagram, and cross-sectional imaging can help further elucidate the underlying etiology and rule out mechanical causes. Treatment is tailored to the underlying cause. Similar to achalasia, treatment targeting lower esophageal sphincter disruption like pneumatic dilation, peroral endoscopic myotomy, and botulinum injection are used in patients with functional EGJOO and persistent symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.