Evidence map›Paper›PMID 30700928›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2018

Incorporation of circulating tumor cells and whole-body metabolic tumor volume of

Lei Fu, Ying Zhu, Wang Jing, Dong Guo, Li Kong, Jinming Yu

Abstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Prognostic Value ofDiagnostics (Basel, Switzerland) · 2021
    Review
  11. European journal of hybrid imaging · 2020
    Article
  12. Article
  13. EpCAMDisease markers · 2019
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Lei FuDepartment of Clinical Medicine, Weifang Medical University, Weifang 261000, China.
Ying ZhuDepartment of Clinical Medicine, Weifang Medical University, Weifang 261000, China.
Wang JingDepartment of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China.
Dong GuoDepartment of Clinical Medicine, Weifang Medical University, Weifang 261000, China.
Li KongDepartment of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China.
Jinming YuDepartment of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China.
Shandong University · CNShandong First Medical University · CNShandong Tumor Hospital · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe investigated the correlation between the number of circulating tumor cells (CTCs) and whole-body metabolic tumor volume (WBMTV) measured by

methodsOne hundred and twenty-nine patients were enrolled in this study. All patients were treated with four cycles of a platinum-based regimen and concurrent chest irradiation, followed by prophylactic cranial irradiation. Blood samples for CTC analysis were obtained from 112 patients before the initiation of chemotherapy (as a baseline), after cycle 1 and after cycle 4. CTCs were measured using the CELLSEARCH

resultsThe number of CTCs at baseline did not correlate with WBMTV before the initiation of therapy (P=0.241). The number of CTCs at baseline and the WBMTV before the initiation of therapy were independent relevant factors for PFS and OS. The subgroup analysis (Group A: CTC count >19.5 and a WBMTV >266.5 cm

conclusionsCTC number and WBMTV are related to progression and death in patients with SCLC. The incorporation of CTC number and WBMTV scans can provide a detailed prognostic prediction for SCLC.

Indexed as

circulating tumor cellPET-CTprognosisSmall-cell lung cancerwhole-body metabolic tumor volume

Identifiers

PMID30700928
PMCPMC6328501
OpenAlexW2908579960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.