Evidence map›Paper›PMID 30700922›Full record

ArticleColombia medica (Cali, Colombia)2018

Sodium thiosulfate and pamidronate for treatment of calciphylaxis: case report.

Sonia Fernández Cañabate, Cristina Lucas Alvarez, Luis Ortega Valin, Jorge Estifan Ksabji

Open access · greenAbstract readCase Reports
In one paragraph

Article in Colombia medica (Cali, Colombia), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sonia Fernández CañabateComplejo Asistencial Universitario de León, Servicio de Farmacia, León, España.
Cristina Lucas AlvarezComplejo Asistencial Universitario de León, Servicio de Nefrología, León, España.
Luis Ortega ValinComplejo Asistencial Universitario de León, Servicio de Farmacia, León, España.
Jorge Estifan KsabjiComplejo Asistencial Universitario de León, Servicio de Nefrología, León, España.
Complejo Asistencial Universitario de Palencia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCalciphylaxis is an infrequent disease that almost exclusively affects patients with chronic kidney disease, although cases have been observed in patients without renal function impairment. The diagnosis is mainly made by clinical manifestations and subsequently confirmed by radiological and histological study. The optimal treatment is not known, although there is a consensus that a multifactorial approach is required. CLINICAL CASE: A 68-year-old woman on hemodialysis for 2 years, who presented a painful nodular lesion in the left thigh, a skin biopsy was performed resulting in a diagnosis of calciphylaxis. TREATMENT AND OUTCOME: Treatment was started with intravenous sodium thiosulfate. Pamidronate is added intravenously, three months later, due to an unfavorable evolution. After 6 months of treatment, improvement in nodular lesions and healing of the ulcerated lesion was observed to be generally well tolerated treatment.

conclusionThe combined treatment of sodium thiosulfate, pamidronate and calcitomimetics has been effectiveand safe for the treatment of calciphylaxis, inducing complete remission.

Indexed as

Administration, IntravenousAgedCalciphylaxisChelating AgentsDrug Therapy, CombinationFemaleHumansKidney Failure, ChronicPamidronateRenal DialysisThiosulfatesTreatment OutcomeChelating AgentsPamidronatesodium thiosulfateThiosulfatesArteriolesCalciphylaxisHyperparathyroidismHyperphosphatemiaHypoalbuminemiapamidronatesodium thiosulfate

Identifiers

PMID30700922
PMCPMC6342083
OpenAlexW2910378189

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.